Literature DB >> 19254898

Isoniazid completion rates for latent tuberculosis infection among college students managed by a community pharmacist.

Karl Hess1, Jeffery Goad, Joanne Wu, Kathleen Johnson.   

Abstract

OBJECTIVE: The authors' objective was to document 9-month and previously recommended 6-month treatment completion rates for latent tuberculosis infection (LTBI) in a pharmacist-managed LTBI clinic in a community pharmacy on a college campus, and to describe patient characteristics. PARTICIPANTS: Participants were university students diagnosed with LTBI.
METHODS: The authors conducted a retrospective review of pharmacy records from 2000 to 2006. Main outcome measures included 6-month and 9-month LTBI treatment completion rates, total isoniazid (INH) tablets taken, characteristics of completers versus noncompleters, average time to treatment completion, and reported adverse drug events.
RESULTS: The 9-month completion rate was 59%, and the 6-month completion rate was 67%. Among those not completing treatment, 15.2% experienced fatigue and 2.2% experienced a rash (p=.04 and p=.03, respectively).
CONCLUSION: LTBI clinics are a unique niche for community pharmacies and can provide individualized patient care to ensure LTBI treatment adherence, monitoring for disease progression, and safety of INH.

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Year:  2009        PMID: 19254898     DOI: 10.3200/JACH.57.5.553-556

Source DB:  PubMed          Journal:  J Am Coll Health        ISSN: 0744-8481


  9 in total

1.  Management of latent tuberculous infection in Norway in 2009: a descriptive cross-sectional study.

Authors:  A I M Olsen; H E Andersen; J Aßmus; J A Djupvik; G Gran; K Skaug; O Mørkve
Journal:  Public Health Action       Date:  2013-06-21

2.  High Rate of Treatment Completion in Program Settings With 12-Dose Weekly Isoniazid and Rifapentine for Latent Mycobacterium tuberculosis Infection.

Authors:  Amy L Sandul; Nwabunie Nwana; J Mike Holcombe; Mark N Lobato; Suzanne Marks; Risa Webb; Shu-Hua Wang; Brock Stewart; Phil Griffin; Garrett Hunt; Neha Shah; Asween Marco; Naveen Patil; Leonard Mukasa; Ruth N Moro; John Jereb; Sundari Mase; Terence Chorba; Sapna Bamrah-Morris; Christine S Ho
Journal:  Clin Infect Dis       Date:  2017-10-01       Impact factor: 9.079

3.  Implementation of Isoniazid Preventive Therapy among People Living with HIV in Northwestern Nigeria: Completion Rate and Predictive Factors.

Authors:  Abiola Victor Adepoju; Chidubem L Ogbudebe; Olusola Adedeji Adejumo; Johnson Okolie; Jude O Inegbeboh
Journal:  J Glob Infect Dis       Date:  2020-05-22

4.  Economics of United States tuberculosis airline contact investigation policies: a return on investment analysis.

Authors:  Margaret S Coleman; Karen J Marienau; Nina Marano; Suzanne M Marks; Martin S Cetron
Journal:  Travel Med Infect Dis       Date:  2013-11-08       Impact factor: 6.211

5.  Toward a generation free of tuberculosis: TB disease and infection in individuals of college age in the United States.

Authors:  N S Shah; A Flood-Bryzman; C Jeffries; J Scott
Journal:  J Am Coll Health       Date:  2017-09-15

6.  Adherence: a review of education, research, practice, and policy in the United States.

Authors:  Nathaniel M Rickles; Todd A Brown; Melissa S Mcgivney; Margie E Snyder; Kelsey A White
Journal:  Pharm Pract (Granada)       Date:  2010-03-15

7.  Treatment completion for latent tuberculosis infection: a retrospective cohort study comparing 9 months of isoniazid, 4 months of rifampin and 3 months of isoniazid and rifapentine.

Authors:  Adelaide H McClintock; McKenna Eastment; Christy M McKinney; Caroline L Pitney; Masahiro Narita; David R Park; Shireesha Dhanireddy; Alexandra Molnar
Journal:  BMC Infect Dis       Date:  2017-02-14       Impact factor: 3.090

8.  Understanding of latent tuberculosis, its treatment and treatment side effects in immigrant and refugee patients.

Authors:  Katie Butcher; Beverley-Ann Biggs; Karin Leder; Chris Lemoh; Daniel O'Brien; Caroline Marshall
Journal:  BMC Res Notes       Date:  2013-08-29

9.  Addressing Latent Tuberculosis Infection Treatment Through a Collaborative Care Model With Community Pharmacies and a Health Department.

Authors:  Bernadette Jakeman; Stefanie J Logothetis; Melissa H Roberts; Amy Bachyrycz; Diana Fortune; Matthew E Borrego; Julianna Ferreira; Marcos Burgos
Journal:  Prev Chronic Dis       Date:  2020-02-13       Impact factor: 2.830

  9 in total

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