| Literature DB >> 1925414 |
T Dörner1, F Hiepe, F Mielke, S T Kiessig, A Lukowsky, E Apostoloff.
Abstract
An enzyme immunoassay was developed to detect anti-Ro(SS-A) autoantibodies. Both Ro-antigen components (52 and 60 kD) were purified from a pig spleen extract, using fast protein liquid chromatography (FPLC). Anti-La, anti-RNP, anti-DNA and anti-Sm antibodies do not react to the purified antigen. There was a strong correlation between anti-Ro activity in EIA and the titers in counter immunoelectrophoresis (rs = 0.893). Anti-Ro antibodies were found in 54 (69.2%) of 78 SLE sera by the developed EIA.Entities:
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Year: 1991 PMID： 1925414 DOI： 10.3109/03009749109096799
Source DB: PubMed Journal: Scand J Rheumatol ISSN： 0300-9742 Impact factor: 3.641