Literature DB >> 19253247

Comparison of 0.5% levobupivacaine, 0.5% bupivacaine, and 2% lidocaine for retrobulbar anesthesia in vitreoretinal surgery.

Recep Aksu1, Cihangir Bicer, Abdullah Ozkiris, Aynur Akin, Adnan Bayram, Adem Boyaci.   

Abstract

PURPOSE: The authors compared the efficacy of local anesthetics levobupivacaine, bupivacaine, and lidocaine for retrobulbar anesthesia in vitreoretinal surgery.
METHODS: A total of 135 patients presenting for vitreoretinal surgery under local anesthesia were included in the study. Patients were randomly allocated to one of three groups. Group LB patients received 5 mL of 0.5% levobupivacaine, Group L patients received 5 mL of 2% lidocaine, and Group B patients received 5 mL of 0.5% bupivacaine for retrobulbar anesthesia via inferotemporal injection. Sensory and motor block durations were recorded. Intraoperative and postoperative pain was assessed by using verbal pain scala. Anesthesia efficiency, patient and surgeon satisfaction, and akinesia were assessed by using point scales. Hemodynamic data and adverse events were recorded.
RESULTS: The demographic characteristics of patients, duration of surgery, and hemodynamic data in both groups were similar. The duration of motor and sensory block was longer in levobupivacaine and bupivacaine groups than lidocaine group. Pain on injection was found more frequent in Group L and Group B than Group LB and the difference between the Groups LB and B was significant (p<0.05). Surgeon and patient satisfaction were also higher and intraoperative pain was less in levobupivacaine group than lidocaine and bupivacaine groups.
CONCLUSIONS: Levobupivacaine provides longer motor and sensory block duration and higher surgeon and patient satisfaction than lidocaine and bupivacaine when used for retrobulbar anesthesia in vitreoretinal surgery.

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Year:  2009        PMID: 19253247     DOI: 10.1177/112067210901900217

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  6 in total

Review 1.  Levobupivacaine: a review of its use in regional anaesthesia and pain management.

Authors:  Mark Sanford; Gillian M Keating
Journal:  Drugs       Date:  2010-04-16       Impact factor: 9.546

Review 2.  Clinical Pharmacokinetics and Pharmacodynamics of Levobupivacaine.

Authors:  Chantal A A Heppolette; Derek Brunnen; Sohail Bampoe; Peter M Odor
Journal:  Clin Pharmacokinet       Date:  2020-06       Impact factor: 6.447

3.  The efficacy of 0.75% levobupivacaine versus 0.75% ropivacaine for peribulbar anesthesia in vitreoretinal surgery.

Authors:  Ashraf M Ghali
Journal:  Saudi J Anaesth       Date:  2012-01

4.  Postoperative Analgesic Efficacy of Sub-Tenon's Block with Levobupivacaine in Retinal Surgery under General Anesthesia.

Authors:  Ola T Abdeldayem; Ghada F Amer; Mohamed G Abdulla
Journal:  Anesth Essays Res       Date:  2019 Jul-Sep

5.  Comparison of levobupivacaine 0.5% or bupivacaine 0.5% both in a mixture with lidocaine 2% for superficial extraconal blockade.

Authors:  Nauman Ahmad; Abdul Zahoor; Abdullah Al Assiri; Sabah Al Jastaneiah; Waleed Riad
Journal:  Middle East Afr J Ophthalmol       Date:  2012 Jul-Sep

6.  Ophthalmic regional anaesthesia: A review and update.

Authors:  Vv Jaichandran
Journal:  Indian J Anaesth       Date:  2013-01
  6 in total

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