Literature DB >> 19252994

Organic synthesis in water: a green protocol for the synthesis of 2-(cyclohexylamino)-3- aryl- indeno[1,2-b]furan-4-ones.

Majid M Heravi1, Bita Baghernejad, Hossein A Oskooie.   

Abstract

Aldehydes, 1,3-indandione and cyclohexylisocyanide undergo smooth coupling-cyclization in water to produce the corresponding 2-(cyclohexylamino)-3-aryl- indeno [1,2-b] furan-4-ones in good yields. Water was used as a solvent to avoid the use of other highly toxic and environmentally unfavorable solvents for this synthesis.

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Year:  2009        PMID： 19252994     DOI： 10.1007/s11030-009-9122-3

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  6 in total

1.  Multicomponent Reactions with Isocyanides.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-09-15       Impact factor: 15.336

2.  Determining the geometries of transition States by use of antihydrophobic additives in water.

Authors:  Ronald Breslow
Journal:  Acc Chem Res       Date:  2004-07       Impact factor: 22.384

3.  A novel one-pot, four component synthesis of some densely functionalized pyrroles.

Authors:  Javad Azizian; Ali R Karimi; Hamedeh Arefrad; Ali A Mohammadi; M R Mohammadizadeh
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943

Review 4.  Recent developments in isocyanide based multicomponent reactions in applied chemistry.

Authors:  Alexander Dömling
Journal:  Chem Rev       Date:  2006-01       Impact factor: 60.622

5.  Organic reactions in aqueous media with a focus on carbon-carbon bond formations: a decade update.

Authors:  Chao-Jun Li
Journal:  Chem Rev       Date:  2005-08       Impact factor: 60.622

6.  2-Arylindenes and 2-arylindenones: molecular structures and considerations in the binding orientation of unsymmetrical nonsteroidal ligands to the estrogen receptor.

Authors:  G M Anstead; S R Wilson; J A Katzenellenbogen
Journal:  J Med Chem       Date:  1989-09       Impact factor: 7.446
  6 in total
  2 in total

Review 1.  The molecular diversity scope of 1,3-indandione in organic synthesis.

Authors:  Shima Asadi; Ghodsi Mohammadi Ziarani
Journal:  Mol Divers       Date:  2015-05-10       Impact factor: 2.943

Review 2.  Isocyanide-Based Multicomponent Reactions in Water: Advanced Green Tools for the Synthesis of Heterocyclic Compounds.

Authors:  Siamak Javanbakht; Mohammad Taghi Nazeri; Hassan Farhid; Tahereh Nasiriani; Vida Khodkari; Ahmad Shaabani
Journal:  Top Curr Chem (Cham)       Date:  2022-09-22
  2 in total

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