Literature DB >> 19251316

Quantum dots-based immunofluorescence technology for the quantitative determination of HER2 expression in breast cancer.

Chuang Chen1, Jun Peng, He-Shun Xia, Gui-Fang Yang, Qiong-Shui Wu, Liang-Dong Chen, Li-Bo Zeng, Zhi-Ling Zhang, Dai-Wen Pang, Yan Li.   

Abstract

HER2 detection is important for breast cancer (BC) treatment and prognosis, but the detection methods currently used have some disadvantages. Quantum dots (QDs)-based probes provide a potentially important new method for HER2 detection in clinical practice. This potential is examined in this paper. A QDs HER2 probe kit and QDs image acquisition and analysis software were developed and applied to 94 clinical samples of BC. Compared to conventional immunohistochemistry techniques, this method provided a superior accurate and sensitive method for the detection of HER2 in clinical breast cancer diagnosis.

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Year:  2009        PMID： 19251316     DOI： 10.1016/j.biomaterials.2009.02.010

Source DB:  PubMed          Journal:  Biomaterials        ISSN： 0142-9612            Impact factor:   12.479


  45 in total

1.  Conjugates of folic acids with BSA-coated quantum dots for cancer cell targeting and imaging by single-photon and two-photon excitation.

Authors:  He Meng; Ji-Yao Chen; Lan Mi; Pei-Nan Wang; Mei-Ying Ge; Yang Yue; Ning Dai
Journal:  J Biol Inorg Chem       Date:  2010-10-02       Impact factor: 3.358

2.  Analysis of cancer marker in tissues with Hadamard transform fluorescence spectral microscopic imaging.

Authors:  Hao Xu; Chuang Chen; Yue He; Hong-Wu Tang; Zhi-Ling Zhang; Yan Li; Dai-Wen Pang
Journal:  J Fluoresc       Date:  2015-02-07       Impact factor: 2.217

Review 3.  Multiplex bioimaging of single-cell spatial profiles for precision cancer diagnostics and therapeutics.

Authors:  Mayar Allam; Shuangyi Cai; Ahmet F Coskun
Journal:  NPJ Precis Oncol       Date:  2020-05-01

4.  A Novel Fluorescent Quantum Dot Probe for the Rapid Diagnostic High Contrast Imaging of Tumor in Mice.

Authors:  M Vibin; R Vinayakan; F B Fernandez; Annie John; Annie Abraham
Journal:  J Fluoresc       Date:  2016-12-05       Impact factor: 2.217

Review 5.  Comparison of quantum dot immunofluorescence histochemistry with conventional immunohistochemistry in detecting Helicobacter pylori infection in paraffin-embedded tissues of gastric biopsy.

Authors:  Weisong Wan; Qinxue Pu; Xin Huang; Daizhen Luo; Yuchang Hu; Yufei Liu
Journal:  J Mol Histol       Date:  2021-01-08       Impact factor: 2.611

Review 6.  Quantum dots for quantitative imaging: from single molecules to tissue.

Authors:  Tania Q Vu; Wai Yan Lam; Ellen W Hatch; Diane S Lidke
Journal:  Cell Tissue Res       Date:  2015-01-27       Impact factor: 5.249

7.  Quantum dot-based in situ simultaneous molecular imaging and quantitative analysis of EGFR and collagen IV and identification of their prognostic value in triple-negative breast cancer.

Authors:  Hong-Mei Zheng; Chuang Chen; Xin-Hong Wu; Jian Chen; Si Sun; Jin-Zhong Sun; Ming-Wei Wang; Sheng-Rong Sun
Journal:  Tumour Biol       Date:  2015-09-19

8.  Comparison of quantum dots immunofluorescence histochemistry and conventional immunohistochemistry for the detection of caveolin-1 and PCNA in the lung cancer tissue microarray.

Authors:  Honglei Chen; Jingling Xue; Yuxia Zhang; Xiaobo Zhu; Jun Gao; Baoping Yu
Journal:  J Mol Histol       Date:  2009-11-12       Impact factor: 2.611

Review 9.  Semiconductor quantum dots for bioimaging and biodiagnostic applications.

Authors:  Brad A Kairdolf; Andrew M Smith; Todd H Stokes; May D Wang; Andrew N Young; Shuming Nie
Journal:  Annu Rev Anal Chem (Palo Alto Calif)       Date:  2013-03-20       Impact factor: 10.745

10.  Accurate sensitivity of quantum dots for detection of HER2 expression in breast cancer cells and tissues.

Authors:  Akram-Sadat Tabatabaei-Panah; Mahmood Jeddi-Tehrani; Roya Ghods; Mohammad-Mehdi Akhondi; Nazanin Mojtabavi; Ahmad-Reza Mahmoudi; Ebrahim Mirzadegan; Sorour Shojaeian; Amir-Hassan Zarnani
Journal:  J Fluoresc       Date:  2012-12-05       Impact factor: 2.217
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