Literature DB >> 19250930

Stability of analytes related to clinical chemistry and bone metabolism in blood specimens after delayed processing.

Sara R Zwart1, Megan Wolf, Ann Rogers, Shanna Rodgers, Patti L Gillman, Kristen Hitchcox, Karen L Ericson, Scott M Smith.   

Abstract

OBJECTIVES: We investigated the stability of 36 analytes related to clinical chemistry in a controlled storage study. DESIGN AND METHODS: Blood was collected from 11 subjects and was maintained for 45 min, 2.5 h, 5 h, or 24 h after phlebotomy before centrifugation.
RESULTS: Statistically significant changes were observed only for parathyroid hormone, osteocalcin, zinc, pyridoxal 5'-phosphate, and homocysteine.
CONCLUSIONS: These studies indicate that many analytes in clinical chemistry are stable for 24 h before centrifugation.

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Year:  2009        PMID: 19250930     DOI: 10.1016/j.clinbiochem.2009.02.010

Source DB:  PubMed          Journal:  Clin Biochem        ISSN: 0009-9120            Impact factor:   3.281


  5 in total

1.  Effects of Transport Temperature on the Stability of Inflammatory, Hemostasis, Endothelial Function, and Oxidative Stress Plasma Biomarker Concentrations.

Authors:  Octavia M Peck Palmer; Melinda Carter; Chung-Chou H Chang; Nicole Lucko; Vanessa M Jackson; Qian Sun; Xinyan Xie; Melanie Scott; John A Kellum; Arvind Venkat; Sachin Yende
Journal:  Shock       Date:  2017-06       Impact factor: 3.454

Review 2.  Steroid assays in paediatric endocrinology.

Authors:  John W Honour
Journal:  J Clin Res Pediatr Endocrinol       Date:  2010-02-01

3.  Improving Science by Overcoming Laboratory Pitfalls With Hormone Measurements.

Authors:  Jacquelien J Hillebrand; Wjera V Wickenhagen; Annemieke C Heijboer
Journal:  J Clin Endocrinol Metab       Date:  2021-03-25       Impact factor: 5.958

4.  The impact of pre-analytical variations on biochemical analytes stability: A systematic review.

Authors:  Mehdi Hedayati; S Adeleh Razavi; Seti Boroomand; Sima Kheradmand Kia
Journal:  J Clin Lab Anal       Date:  2020-09-01       Impact factor: 3.124

5.  Delayed Processing of Chilled Whole Blood for 24 Hours Does Not Affect the Concentration of the Majority of Micronutrient Status Biomarkers.

Authors:  Kerry S Jones; Sarah R Meadows; Karen Chamberlain; Damon A Parkington; Dave Collins; Polly Page; Albert Koulman
Journal:  J Nutr       Date:  2021-11-02       Impact factor: 4.798

  5 in total

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