Literature DB >> 19249139

[Sarcoidosis-like granulomatosis revealing a tertiary syphilis].

B Hervier1, H Wastiaux, T Freour, A Masseau, S Corvec, T Armingeat, M Hamidou.   

Abstract

Numerous disorders can cause a systemic granulomatosis. We report a patient who presented a biopsy proven granulomatous skin eruption, fever, and atypical thoracic pain. Electrocardiogram showed a first-degree atrioventricular heart bloc. During follow-up he developed a panuveitis and oral corticosteroids were started. A diagnosis of systemic sarcoidosis was considered. Because of unfavourable ophthalmologic outcome, investigations were enlarged and revealed a highly positive serology for syphilis and VDRL both in serum and cerebrospinal fluid. Clinical outcome with penicillin G therapy was favorable. This observation reminds us the clinical polymorphism of syphilis, which can be presented as a systemic granulomatosis.

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Year:  2009        PMID: 19249139     DOI: 10.1016/j.revmed.2009.01.003

Source DB:  PubMed          Journal:  Rev Med Interne        ISSN: 0248-8663            Impact factor:   0.728


  2 in total

Review 1.  The immunopathobiology of syphilis: the manifestations and course of syphilis are determined by the level of delayed-type hypersensitivity.

Authors:  J Andrew Carlson; Ganary Dabiri; Bernard Cribier; Stewart Sell
Journal:  Am J Dermatopathol       Date:  2011-07       Impact factor: 1.533

2.  Solitary cavernous sinus neurosarcoidosis mimicking neurosyphilis.

Authors:  Dong Ha Kim; Won Ho Cho; Kyu Sup Cho; Seong Heon Cha
Journal:  J Korean Neurosurg Soc       Date:  2014-01-31
  2 in total

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