Literature DB >> 19247732

The role of Kv3-type potassium channels in cerebellar physiology and behavior.

Rolf H Joho1, Edward C Hurlock.   

Abstract

Different subunits of the Kv3 subfamily of voltage-gated potassium (Kv) channels (Kv3.1-Kv3.4) are expressed in distinct neuronal subpopulations in the cerebellum. Behavioral phenotypes in Kv3-null mutant mice such as ataxia with prominent hypermetria and heightened alcohol sensitivity are characteristic of cerebellar dysfunction. Here, we review how the unique biophysical properties of Kv3-type potassium channels, fast activation and fast deactivation that enable cerebellar neurons to generate brief action potentials at high frequencies, affect firing patterns and influence cerebellum-mediated behavior.

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Year:  2009        PMID： 19247732     DOI： 10.1007/s12311-009-0098-4

Source DB:  PubMed          Journal:  Cerebellum        ISSN： 1473-4222            Impact factor:   3.847


  74 in total

1.  Maintenance of high-frequency transmission at purkinje to cerebellar nuclear synapses by spillover from boutons with multiple release sites.

Authors:  Petra Telgkamp; Daniel E Padgett; Veronica A Ledoux; Catherine S Woolley; Indira M Raman
Journal:  Neuron       Date:  2004-01-08       Impact factor: 17.173

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Journal:  J Neurophysiol       Date:  2008-09-03       Impact factor: 2.714

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Journal:  Proc Natl Acad Sci U S A       Date:  1997-02-18       Impact factor: 11.205

Review 4.  The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function.

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Journal:  Science       Date:  1988-12-23       Impact factor: 47.728

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Journal:  Brain Res       Date:  1971-08-07       Impact factor: 3.252

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7.  Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes.

Authors:  Michael F Waters; Natali A Minassian; Giovanni Stevanin; Karla P Figueroa; John P A Bannister; Dagmar Nolte; Allan F Mock; Virgilio Gerald H Evidente; Dominic B Fee; Ulrich Müller; Alexandra Dürr; Alexis Brice; Diane M Papazian; Stefan M Pulst
Journal:  Nat Genet       Date:  2006-02-26       Impact factor: 38.330

8.  Ultrastructural localization of Shaker-related potassium channel subunits and synapse-associated protein 90 to septate-like junctions in rat cerebellar Pinceaux.

Authors:  G Laube; J Röper; J C Pitt; S Sewing; U Kistner; C C Garner; O Pongs; R W Veh
Journal:  Brain Res Mol Brain Res       Date:  1996-11

9.  Allele-dependent changes of olivocerebellar circuit properties in the absence of the voltage-gated potassium channels Kv3.1 and Kv3.3.

Authors:  Anne McMahon; Stephen C Fowler; Teresa M Perney; Walther Akemann; Thomas Knöpfel; Rolf H Joho
Journal:  Eur J Neurosci       Date:  2004-06       Impact factor: 3.386

10.  Kv3.3 channels at the Purkinje cell soma are necessary for generation of the classical complex spike waveform.

Authors:  Edward Zagha; Eric J Lang; Bernardo Rudy
Journal:  J Neurosci       Date:  2008-02-06       Impact factor: 6.167
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  24 in total

1.  KCNC3(R420H), a K(+) channel mutation causative in spinocerebellar ataxia 13 displays aberrant intracellular trafficking.

Authors:  Carolina Gallego-Iradi; Justin S Bickford; Swati Khare; Alexis Hall; Jerelyn A Nick; Donya Salmasinia; Kolja Wawrowsky; Serguei Bannykh; Duong P Huynh; Diego E Rincon-Limas; Stefan M Pulst; Harry S Nick; Pedro Fernandez-Funez; Michael F Waters
Journal:  Neurobiol Dis       Date:  2014-08-22       Impact factor: 5.996

2.  Fast delayed rectifier potassium current: critical for input and output of the circadian system.

Authors:  Takashi Kudo; Dawn H Loh; Dika Kuljis; Cara Constance; Christopher S Colwell
Journal:  J Neurosci       Date:  2011-02-23       Impact factor: 6.167

3.  Dendritic Kv3.3 potassium channels in cerebellar purkinje cells regulate generation and spatial dynamics of dendritic Ca2+ spikes.

Authors:  Edward Zagha; Satoshi Manita; William N Ross; Bernardo Rudy
Journal:  J Neurophysiol       Date:  2010-03-31       Impact factor: 2.714

4.  Deletion of Class II ADP-Ribosylation Factors in Mice Causes Tremor by the Nav1.6 Loss in Cerebellar Purkinje Cell Axon Initial Segments.

Authors:  Nobutake Hosoi; Koji Shibasaki; Mayu Hosono; Ayumu Konno; Yo Shinoda; Hiroshi Kiyonari; Kenichi Inoue; Shin-Ichi Muramatsu; Yasuki Ishizaki; Hirokazu Hirai; Teiichi Furuichi; Tetsushi Sadakata
Journal:  J Neurosci       Date:  2019-06-14       Impact factor: 6.167

Review 5.  Kv3 Channels: Enablers of Rapid Firing, Neurotransmitter Release, and Neuronal Endurance.

Authors:  Leonard K Kaczmarek; Yalan Zhang
Journal:  Physiol Rev       Date:  2017-10-01       Impact factor: 37.312

6.  Vasoactive intestinal peptide produces long-lasting changes in neural activity in the suprachiasmatic nucleus.

Authors:  Takashi Kudo; Yu Tahara; Karen L Gamble; Douglas G McMahon; Gene D Block; Christopher S Colwell
Journal:  J Neurophysiol       Date:  2013-06-05       Impact factor: 2.714

7.  Diverse precerebellar neurons share similar intrinsic excitability.

Authors:  Kristine E Kolkman; Lauren E McElvain; Sascha du Lac
Journal:  J Neurosci       Date:  2011-11-16       Impact factor: 6.167

8.  Rescue of motor coordination by Purkinje cell-targeted restoration of Kv3.3 channels in Kcnc3-null mice requires Kcnc1.

Authors:  Edward C Hurlock; Mitali Bose; Ganon Pierce; Rolf H Joho
Journal:  J Neurosci       Date:  2009-12-16       Impact factor: 6.167

9.  Functional effects of spinocerebellar ataxia type 13 mutations are conserved in zebrafish Kv3.3 channels.

Authors:  Allan F Mock; Jessica L Richardson; Jui-Yi Hsieh; Gina Rinetti; Diane M Papazian
Journal:  BMC Neurosci       Date:  2010-08-16       Impact factor: 3.288

10.  Human ataxias: a genetic dissection of inositol triphosphate receptor (ITPR1)-dependent signaling.

Authors:  Stephanie Schorge; Joyce van de Leemput; Andrew Singleton; Henry Houlden; John Hardy
Journal:  Trends Neurosci       Date:  2010-03-11       Impact factor: 13.837
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