Literature DB >> 19247390

An investigation of intraocular lens damage and foreign bodies using an injectable hydrophilic acrylic lens implant.

S Harsum1, S Mann, I Clatworthy, J Lewin, B Little.   

Abstract

AIMS: To determine the nature of intraocular lens (IOL) surface abnormalities seen after the injection of hydrophilic acrylic lenses (Rayner C-flex 570C), through their accompanying pre-packaged disposable injectors. Hexagonal and round nozzle injectors from the same lens manufacturer were compared.
METHODS: A series of lenses were injected into a petri dish, using two different manufacturer-supplied disposable injectors. The injector nozzle, plunger, and IOL were subsequently examined by light and scanning electron microscopy (SEM) for defects.
RESULTS: When using the hexagonal nozzle, eight out of nine lenses had linear surface abnormalities along the posterior surface of the IOL in the direction of injection. These abnormalities appeared to be scratches on the surface of the IOL and there were no corresponding defects on the nozzle. A newly introduced injector, with an oval nozzle and a larger compressible plunger, eliminated the vast majority of these surface abnormalities.
CONCLUSIONS: Manufacturer-supplied hexagonal nozzle injectors, but not oval nozzle injectors, produce linear scratches on the posterior surface of the IOL. These scratches did not disappear with time in vivo.

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Mesh:

Year:  2009        PMID: 19247390     DOI: 10.1038/eye.2009.3

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  3 in total

1.  An implantable microfluidic device for self-monitoring of intraocular pressure.

Authors:  Ismail E Araci; Baolong Su; Stephen R Quake; Yossi Mandel
Journal:  Nat Med       Date:  2014-08-24       Impact factor: 53.440

2.  Comparison of incision size and intraocular lens performance after implantation with three preloaded systems and one manual delivery system.

Authors:  Javier Mendicute; Thierry Amzallag; Lixin Wang; Aldo A Martinez
Journal:  Clin Ophthalmol       Date:  2018-08-21

3.  A laboratory evaluation of nozzle tip damage in four generations of intraocular lens injector systems using a self-developed damage scale.

Authors:  Hui Fang; Lu Zhang; Sonja Schickhardt; Patrick R Merz; Weijia Yan; Mélanie Leroux; Gerd U Auffarth
Journal:  Sci Rep       Date:  2022-02-17       Impact factor: 4.379

  3 in total

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