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Literature DB >> 19243175

Development of the renal glucose reabsorption inhibitors: a new mechanism for the pharmacotherapy of diabetes mellitus type 2.

William N Washburn¹.

Abstract

Entities: Chemical Disease

Mesh：

Substances：

Year: 2009 PMID： 19243175 DOI： 10.1021/jm8013019

Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446

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25 in total

Review 1. Renal glucose transporters: novel targets for hyperglycemia management.

Authors: Amanda Mather; Carol Pollock
Journal: Nat Rev Nephrol Date: 2010-03-30 Impact factor: 28.314

2. Structural selectivity of human SGLT inhibitors.

Authors: Charles S Hummel; Chuan Lu; Jie Liu; Chiari Ghezzi; Bruce A Hirayama; Donald D F Loo; Vladimir Kepe; Jorge R Barrio; Ernest M Wright
Journal: Am J Physiol Cell Physiol Date: 2011-09-21 Impact factor: 4.249

3. A specific pharmacophore model of sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.

Authors: Chunlei Tang; Xiaoyun Zhu; Dandan Huang; Xin Zan; Baowei Yang; Ying Li; Xiaoyong Du; Hai Qian; Wenlong Huang
Journal: J Mol Model Date: 2011-11-27 Impact factor: 1.810

4. Synthesis and SAR of Thiazolylmethylphenyl Glucoside as Novel C-Aryl Glucoside SGLT2 Inhibitors.

Authors: Kwang-Seop Song; Suk Ho Lee; Min Ju Kim; Hee Jeong Seo; Junwon Lee; Sung-Han Lee; Myung Eun Jung; Eun-Jung Son; MinWoo Lee; Jeongmin Kim; Jinhwa Lee
Journal: ACS Med Chem Lett Date: 2010-12-13 Impact factor: 4.345

5. SHR3824, a novel selective inhibitor of renal sodium glucose cotransporter 2, exhibits antidiabetic efficacy in rodent models.

Authors: Pang-ke Yan; Li-na Zhang; Ying Feng; Hui Qu; Li Qin; Lian-shan Zhang; Ying Leng
Journal: Acta Pharmacol Sin Date: 2014-05 Impact factor: 6.150

10. Enantioselective synthesis of beta-(3-hydroxypyrazol-1-yl) ketones using an organocatalyzed Michael addition reaction.

Authors: Sanjib Gogoi; Cong-Gui Zhao; Derong Ding
Journal: Org Lett Date: 2009-06-04 Impact factor: 6.005

Development of the renal glucose reabsorption inhibitors: a new mechanism for the pharmacotherapy of diabetes mellitus type 2.

Review 1. Renal glucose transporters: novel targets for hyperglycemia management.

2. Structural selectivity of human SGLT inhibitors.

3. A specific pharmacophore model of sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.

4. Synthesis and SAR of Thiazolylmethylphenyl Glucoside as Novel C-Aryl Glucoside SGLT2 Inhibitors.

5. SHR3824, a novel selective inhibitor of renal sodium glucose cotransporter 2, exhibits antidiabetic efficacy in rodent models.

6. Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

Review 7. Sodium-glucose cotransporter 2 (SGLT-2) inhibitors: a new antidiabetic drug class.

Review 8. SGLT2 Inhibitors: Physiology and Pharmacology.

Review 9. Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus.

10. Enantioselective synthesis of beta-(3-hydroxypyrazol-1-yl) ketones using an organocatalyzed Michael addition reaction.