| Literature DB >> 19241407 |
Edith H M Lempens1, Brett A Helms, Maarten Merkx, E W Meijer.
Abstract
Site-specific immobilization of peptides and proteins is crucial to ensure their functionality in surface-based assays. We report the use of aniline-catalyzed oxime ligations as a very efficient and broadly applicable method to covalently attach the N terminus of proteins and peptides to a surface functionalized with alkoxy-amine groups.Entities:
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Year: 2009 PMID: 19241407 DOI: 10.1002/cbic.200900028
Source DB: PubMed Journal: Chembiochem ISSN: 1439-4227 Impact factor: 3.164