Literature DB >> 19240819

Intravenous administration of iron sucrose for treating anemia in postpartum women.

C Giannoulis1, A Daniilidis, T Tantanasis, K Dinas, J Tzafettas.   

Abstract

BACKGROUND: To compare the efficacy of oral and intravenous administration of iron supplements for treating postpartum anemia.
METHODS: One hundred and four anemic postpartum women were studied prospectively. The criteria for the diagnosis of anemia were Hb<8 gr/dl and ferritine<10 microg/dl. They were randomised into two groups. Group A consisted of 78 women who received i.v. a total amount of 300 mg iron sucrose in three days. Group B consisted of 26 women, who received orally 800 mg iron proteinsuccinylate daily for four weeks.
RESULTS: At the end of the study, in group A the increase of Hb mean level was 4.6 gr/dl and of ferritin mean level was 105 mg/L. In group B the increase in hemoglobin mean level was 2.3 gr/dl and ferritin mean level was 68 mg/L. There was significant difference in the increase of hemoglobin level (p=0.0001) and also in the increase in ferritin level (p=0.0004) between the two groups.
CONCLUSION: Intravenous administration of iron sucrose seems to be safe and it helps postpartum women to recover early from anemia.

Entities:  

Keywords:  anemia; iron proteinsuccinylate; iron sucrose; pregnancy

Year:  2009        PMID: 19240819      PMCID: PMC2633251     

Source DB:  PubMed          Journal:  Hippokratia        ISSN: 1108-4189            Impact factor:   0.471


  11 in total

1.  [How to avoid transfusion in the post-partum period: importance of an intravenous iron supplement].

Authors:  A Gravier; G Descargues; L Marpeau
Journal:  J Gynecol Obstet Biol Reprod (Paris)       Date:  1999-02

2.  Treatment of iron deficiency anaemia in pregnancy and postpartum with special focus on intravenous iron sucrose complex.

Authors:  Christian Breymann
Journal:  J Med Assoc Thai       Date:  2005-10

3.  Intravenous iron sucrose complex in the treatment of iron deficiency anemia during pregnancy.

Authors:  A K al-Momen; A al-Meshari; L al-Nuaim; A Saddique; Z Abotalib; T Khashogji; M Abbas
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  1996-11       Impact factor: 2.435

Review 4.  Iron status and iron balance during pregnancy. A critical reappraisal of iron supplementation.

Authors:  N Milman; T Bergholt; K E Byg; L Eriksen; N Graudal
Journal:  Acta Obstet Gynecol Scand       Date:  1999-10       Impact factor: 3.636

5.  Effect of postpartum iron supplementation on red cell and iron parameters in non-anaemic iron-deficient women: a randomised placebo-controlled study.

Authors:  A Krafft; G Perewusnyk; E Hänseler; K Quack; R Huch; C Breymann
Journal:  BJOG       Date:  2005-04       Impact factor: 6.531

6.  Intravenous versus oral iron therapy for postpartum anaemia.

Authors:  N Bhandal; R Russell
Journal:  BJOG       Date:  2006-09-27       Impact factor: 6.531

7.  Intravenous versus oral iron for treatment of anemia in pregnancy: a randomized trial.

Authors:  Ragip A Al; Eylem Unlubilgin; Omer Kandemir; Serdar Yalvac; Leyla Cakir; Ali Haberal
Journal:  Obstet Gynecol       Date:  2005-12       Impact factor: 7.661

Review 8.  Anemia during pregnancy and treatment with intravenous iron: review of the literature.

Authors:  A Bashiri; E Burstein; E Sheiner; M Mazor
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2003-09-10       Impact factor: 2.435

9.  [Acute postpartum anaemia. Clinical practice and interest of intravenous iron].

Authors:  D-E Broche; C Gay; S Armand-Branger; L Grangeasse; J-J Terzibachian
Journal:  Gynecol Obstet Fertil       Date:  2004 Jul-Aug

Review 10.  Parenteral iron therapy in obstetrics: 8 years experience with iron-sucrose complex.

Authors:  G Perewusnyk; R Huch; A Huch; C Breymann
Journal:  Br J Nutr       Date:  2002-07       Impact factor: 3.718

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  11 in total

1.  Oral vs intravenous iron therapy for postpartum anemia: a systematic review and meta-analysis.

Authors:  Pervez Sultan; Sohail Bampoe; Raj Shah; Nan Guo; Jaclyn Estes; Christopher Stave; Lawrence Tim Goodnough; Stephen Halpern; Alex James Butwick
Journal:  Am J Obstet Gynecol       Date:  2018-12-19       Impact factor: 8.661

2.  Effectiveness of intravenous iron sucrose in management of iron-deficient anemia of pregnancy at rural hospital set up.

Authors:  Deepti Shrivastava; Sunetra Inamdar; Sindhu Bhute; Amreen Singh
Journal:  J Obstet Gynaecol India       Date:  2012-06-01

3.  Oral versus intravenous iron therapy in iron deficiency anemia: An observational study.

Authors:  Samarendra N Das; Amruta Devi; Bibhuti B Mohanta; Anurag Choudhury; Abinash Swain; Pravat K Thatoi
Journal:  J Family Med Prim Care       Date:  2020-07-30

Review 4.  Treatment for women with postpartum iron deficiency anaemia.

Authors:  Veronika Markova; Astrid Norgaard; Karsten Juhl Jørgensen; Jens Langhoff-Roos
Journal:  Cochrane Database Syst Rev       Date:  2015-08-13

5.  The challenges of meeting the blood transfusion requirements in Sub-Saharan Africa: the need for the development of alternatives to allogenic blood.

Authors:  Erhabor Osaro; Adias Teddy Charles
Journal:  J Blood Med       Date:  2011-02-06

6.  Ferric carboxymaltose: A revolution in the treatment of postpartum anemia in Indian women.

Authors:  Setu Rathod; Sunil K Samal; Purna C Mahapatra; Sunita Samal
Journal:  Int J Appl Basic Med Res       Date:  2015 Jan-Apr

7.  Long-term efficacy of postpartum intravenous iron therapy.

Authors:  Nadine Becuzzi; Roland Zimmermann; Alexander Krafft
Journal:  Biomed Res Int       Date:  2014-11-06       Impact factor: 3.411

8.  Effectiveness and safety of ferric carboxymaltose compared to iron sucrose in women with iron deficiency anemia: phase IV clinical trials.

Authors:  Amreen Naqash; Rifat Ara; Ghulam N Bader
Journal:  BMC Womens Health       Date:  2018-01-05       Impact factor: 2.809

9.  Pharmaceutical stability of colloidal saccharated iron oxide injection in normal saline.

Authors:  Daiki Hira; Asami Suzuki; Yusuke Kono; Kosuke Shimokawa; Serika Matsuoka; Ken-Yuh Hasumoto; Hiroyuki Kawahara; Masahide Onoue; Takuya Fujita; Tomonobu Okano; Mikio Kakumoto
Journal:  J Pharm Health Care Sci       Date:  2018-07-25

Review 10.  Iron Sucrose: A Wealth of Experience in Treating Iron Deficiency.

Authors:  Iain C Macdougall; Josep Comin-Colet; Christian Breymann; Donat R Spahn; Ioannis E Koutroubakis
Journal:  Adv Ther       Date:  2020-04-15       Impact factor: 3.845

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