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Literature DB >> 19239879

MicroRNAs and cancer: short RNAs go a long way.

Abstract

MicroRNAs (miRNAs) may be important regulators of gene expression. By modulating oncogenic and tumor suppressor pathways they could, in principle, contribute to tumorigenesis. Consistent with this hypothesis, recurrent genetic and epigenetic alterations of individual miRNAs are found in some tumors. Functional studies are now elucidating the mechanism of action of putative oncogenic and tumor suppressor miRNAs.

Entities: Chemical

Mesh：

Substances：

Year: 2009 PMID： 19239879 PMCID： PMC3910108 DOI： 10.1016/j.cell.2009.02.005

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

93 in total

Review 1. Epigenetic activation of tumor suppressor microRNAs in human cancer cells.

Authors: Yoshimasa Saito; Peter A Jones
Journal: Cell Cycle Date: 2006-10-01 Impact factor: 4.534

2. miR-15 and miR-16 induce apoptosis by targeting BCL2.

Authors: Amelia Cimmino; George Adrian Calin; Muller Fabbri; Marilena V Iorio; Manuela Ferracin; Masayoshi Shimizu; Sylwia E Wojcik; Rami I Aqeilan; Simona Zupo; Mariella Dono; Laura Rassenti; Hansjuerg Alder; Stefano Volinia; Chang-Gong Liu; Thomas J Kipps; Massimo Negrini; Carlo M Croce
Journal: Proc Natl Acad Sci U S A Date: 2005-09-15 Impact factor: 11.205

3. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes.

Authors: Philippe Bouillet; Jared F Purton; Dale I Godfrey; Li-Chen Zhang; Leigh Coultas; Hamsa Puthalakath; Marc Pellegrini; Suzanne Cory; Jerry M Adams; Andreas Strasser
Journal: Nature Date: 2002-02-21 Impact factor: 49.962

4. Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215.

Authors: Sara A Georges; Matthew C Biery; Soo-Yeon Kim; Janell M Schelter; Jane Guo; Aaron N Chang; Aimee L Jackson; Michael O Carleton; Peter S Linsley; Michele A Cleary; B Nelson Chau
Journal: Cancer Res Date: 2008-12-15 Impact factor: 12.701

5. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.

Authors: Sun-Mi Park; Arti B Gaur; Ernst Lengyel; Marcus E Peter
Journal: Genes Dev Date: 2008-04-01 Impact factor: 11.361

6. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer.

Authors: Li Ma; Julie Teruya-Feldstein; Robert A Weinberg
Journal: Nature Date: 2007-09-26 Impact factor: 49.962

7. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma.

Authors: Aaron J Schetter; Suet Yi Leung; Jane J Sohn; Krista A Zanetti; Elise D Bowman; Nozomu Yanaihara; Siu Tsan Yuen; Tsun Leung Chan; Dora L W Kwong; Gordon K H Au; Chang-Gong Liu; George A Calin; Carlo M Croce; Curtis C Harris
Journal: JAMA Date: 2008-01-30 Impact factor: 56.272

8. MYCN regulates oncogenic MicroRNAs in neuroblastoma.

Authors: Johannes H Schulte; Sebastian Horn; Tobias Otto; Birgit Samans; Lukas C Heukamp; Ursula-Christa Eilers; Michael Krause; Kathy Astrahantseff; Ludger Klein-Hitpass; Reinhard Buettner; Alexander Schramm; Holger Christiansen; Martin Eilers; Angelika Eggert; Bernd Berwanger
Journal: Int J Cancer Date: 2008-02-01 Impact factor: 7.396

9. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells.

Authors: Elena Vigorito; Kerry L Perks; Cei Abreu-Goodger; Sam Bunting; Zou Xiang; Susan Kohlhaas; Partha P Das; Eric A Miska; Antony Rodriguez; Allan Bradley; Kenneth G C Smith; Cristina Rada; Anton J Enright; Kai-Michael Toellner; Ian C M Maclennan; Martin Turner
Journal: Immunity Date: 2007-12-06 Impact factor: 31.745

10. Selective blockade of microRNA processing by Lin28.

Authors: Srinivas R Viswanathan; George Q Daley; Richard I Gregory
Journal: Science Date: 2008-02-21 Impact factor: 47.728

406 in total

Review 1. MicroRNAs, wild-type and mutant p53: more questions than answers.

Authors: Matthew Jones; Ashish Lal
Journal: RNA Biol Date: 2012-06-01 Impact factor: 4.652

2. Concurrent suppression of integrin alpha5, radixin, and RhoA phenocopies the effects of miR-31 on metastasis.

Authors: Scott Valastyan; Amelia Chang; Nathan Benaich; Ferenc Reinhardt; Robert A Weinberg
Journal: Cancer Res Date: 2010-06-08 Impact factor: 12.701

3. Identification of microRNAs in the cerebrospinal fluid as biomarker for the diagnosis of glioma.

Authors: Alexander Baraniskin; Jan Kuhnhenn; Uwe Schlegel; Abdelouahid Maghnouj; Hannah Zöllner; Wolf Schmiegel; Stephan Hahn; Roland Schroers
Journal: Neuro Oncol Date: 2011-09-21 Impact factor: 12.300

4. On oncogenes and tumor suppressor genes in the mammary gland.

Authors: Rushika M Perera; Nabeel Bardeesy
Journal: Cold Spring Harb Perspect Biol Date: 2012-06-01 Impact factor: 10.005

5. MicroRNAs in cerebrospinal fluid as biomarker for disease course monitoring in primary central nervous system lymphoma.

Authors: Alexander Baraniskin; Jan Kuhnhenn; Uwe Schlegel; Wolf Schmiegel; Stephan Hahn; Roland Schroers
Journal: J Neurooncol Date: 2012-06-23 Impact factor: 4.130

6. Ratio of miR-196s to HOXC8 messenger RNA correlates with breast cancer cell migration and metastasis.

Authors: Yong Li; Maoxiang Zhang; Huijun Chen; Zheng Dong; Vadivel Ganapathy; Muthusamy Thangaraju; Shuang Huang
Journal: Cancer Res Date: 2010-08-24 Impact factor: 12.701

7. Downregulation of miRNA-15a and miRNA-16 promote tumor proliferation in multiple myeloma by increasing CABIN1 expression.

Authors: Lei Zhang; Lin Zhou; Meng Shi; Yong Kuang; Lei Fang
Journal: Oncol Lett Date: 2017-11-15 Impact factor: 2.967