Literature DB >> 19239228

Microwave-assisted Cu-catalyzed protodecarboxylation of aromatic carboxylic acids.

Lukas J Goossen1, Filipe Manjolinho, Bilal A Khan, Nuria Rodríguez.   

Abstract

An effective protocol has been developed that allows the smooth protodecarboxylation of diversely functionalized aromatic carboxylic acids within 5-15 min. In the presence of at most 5 mol % of an inexpensive catalyst generated in situ from copper(I) oxide and 1,10-phenanthroline, even nonactivated benzoates were converted in high yields and with great preparative ease.

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Year:  2009        PMID: 19239228     DOI: 10.1021/jo802628z

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  4 in total

1.  DFT investigation on the decarboxylation mechanism of ortho hydroxy benzoic acids with acid catalysis.

Authors:  Yanying Hu; Lu Gao; Zhoutong Dai; Guojuan Sun; Tongcun Zhang; Shiru Jia; Yujie Dai; Xiuli Zhang
Journal:  J Mol Model       Date:  2016-02-13       Impact factor: 1.810

2.  Development of a palladium-catalyzed decarboxylative cross-coupling of (2-azaaryl)carboxylates with aryl halides.

Authors:  Christopher K Haley; Christopher D Gilmore; Brian M Stoltz
Journal:  Tetrahedron       Date:  2013-07-08       Impact factor: 2.457

3.  Mild aromatic palladium-catalyzed protodecarboxylation: kinetic assessment of the decarboxylative palladation and the protodepalladation steps.

Authors:  Joshua S Dickstein; John M Curto; Osvaldo Gutierrez; Carol A Mulrooney; Marisa C Kozlowski
Journal:  J Org Chem       Date:  2013-04-29       Impact factor: 4.354

4.  Synthesis and Decarboxylation of Functionalized 2-Pyridone-3-carboxylic Acids and Evaluation of their Antimicrobial Activity and Molecular Docking.

Authors:  Elmira Meghrazi Ahadi; Homa Azizian; Vaezeh Fathi Vavsari; Atousa Aliahmadi; Zeinab Shahsavari; Hamid R Bijanzadeh; Saeed Balalaie
Journal:  Iran J Pharm Res       Date:  2021       Impact factor: 1.696

  4 in total

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