BACKGROUND: Natural orifice transluminal endoscopic surgery has received much attention in recent years. Instead of using prototype devices, we explored the feasibility and practicability of using readily available off-the-shelf devices to perform Natural Orifice Transluminal Endoscopic Surgery in an animal model. METHODS: Twenty pigs underwent transvaginal cholecystectomy, 16 of which were used for surviving study after the procedure. A single-channel endoscope and standard instruments for endoscopic submucosal dissection (hook knife and Insulated Tip knife) were used for cholecystectomy. A single 5-mm laparoscopic port was inserted for gallbladder retraction. RESULTS: Completion of the procedure was achieved in all 20 pigs. In 16 pigs, which were used for surviving study after surgery, 15 survived. Death of 1 pig was due to leakage of urine from the colpotomy and urogenital sinus. Technical success was achieved in the access, dissection, and retrieval of specimen in all the animals. CONCLUSIONS: A hybrid approach with single-channel endoscope together with endoscopic submucosal dissection instruments for transvaginal cholecystectomy was shown to be safe and feasible in this pig model and this serves as a good training model before application of this technique in human. A distinct pattern of complications was identified and needed to be addressed.
BACKGROUND: Natural orifice transluminal endoscopic surgery has received much attention in recent years. Instead of using prototype devices, we explored the feasibility and practicability of using readily available off-the-shelf devices to perform Natural Orifice Transluminal Endoscopic Surgery in an animal model. METHODS: Twenty pigs underwent transvaginal cholecystectomy, 16 of which were used for surviving study after the procedure. A single-channel endoscope and standard instruments for endoscopic submucosal dissection (hook knife and Insulated Tip knife) were used for cholecystectomy. A single 5-mm laparoscopic port was inserted for gallbladder retraction. RESULTS: Completion of the procedure was achieved in all 20 pigs. In 16 pigs, which were used for surviving study after surgery, 15 survived. Death of 1 pig was due to leakage of urine from the colpotomy and urogenital sinus. Technical success was achieved in the access, dissection, and retrieval of specimen in all the animals. CONCLUSIONS: A hybrid approach with single-channel endoscope together with endoscopic submucosal dissection instruments for transvaginal cholecystectomy was shown to be safe and feasible in this pig model and this serves as a good training model before application of this technique in human. A distinct pattern of complications was identified and needed to be addressed.
Authors: Francisco M Sánchez-Margallo; Francisco J Pérez; Miguel A Sánchez; Jaime Bachiller; Alvaro Juárez; Alvaro Serrano; María José Ribal; Antonio Alcaraz Journal: Surg Endosc Date: 2011-10-20 Impact factor: 4.584
Authors: Miguel A Tanimoto; M Lourdes Guerrero; Yoshinori Morita; Jonathan Aguirre-Valadez; Elisa Gomez; Carlos Moctezuma-Velazquez; Jose A Estradas-Trujillo; Miguel A Valdovinos; Luis F Uscanga; Rikiya Fujita Journal: World J Gastrointest Endosc Date: 2015-04-16
Authors: Ki Bum Park; Jun Seok Park; Gyu-Seog Choi; Hye Jin Kim; Soo Yeun Park; Jong Pil Ryuk; Won Ho Choi; You Seok Jang Journal: J Korean Soc Coloproctol Date: 2011-12-31