| Literature DB >> 19237285 |
Eduard Badarau1, Franck Suzenet, Andrzej J Bojarski, Adriana-Luminiţa Fînaru, Gérald Guillaumet.
Abstract
A new group of serotoninergic 5-HT(1A) or 5-HT(7) receptor ligands was identified. These compounds were designed and synthesized on a benzimidazolone scaffold and they enrich the well-known arylpiperazine class of 5-HT ligands. Diverse pharmacomodulations induced a shift in the affinity and selectivity profile with final identification of new potent hits.Entities:
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Year: 2009 PMID： 19237285 DOI： 10.1016/j.bmcl.2009.02.008
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823