Willem de Ronde1. 1. VU University Medical Center, Department of Endocrinology, De Boelelaan 1117, PO Box 7057, 1007 MB Amsterdam, The Netherlands. p.deronde@vumc.nl
Abstract
BACKGROUND: Testosterone supplementation is a standard treatment for young men with hypogonadism and has also been advocated as a treatment for symptomatic older men with low testosterone levels. Several modes of testosterone replacement are available including capsules, patches, injections, buccal tablets and gels. OBJECTIVE: To review the literature concerning therapeutic efficacy and potential limitations of testosterone gels. METHODS: The FDA medical reviews and the computerised database PubMed were searched for clinical trials studying currently approved testosterone gels. RESULTS/ CONCLUSIONS: Testosterone gel has proved to be a valuable contribution to the existing modes of testosterone treatment, combining therapeutic efficacy, convenience and safety.
BACKGROUND:Testosterone supplementation is a standard treatment for young men with hypogonadism and has also been advocated as a treatment for symptomatic older men with low testosterone levels. Several modes of testosterone replacement are available including capsules, patches, injections, buccal tablets and gels. OBJECTIVE: To review the literature concerning therapeutic efficacy and potential limitations of testosterone gels. METHODS: The FDA medical reviews and the computerised database PubMed were searched for clinical trials studying currently approved testosterone gels. RESULTS/ CONCLUSIONS:Testosterone gel has proved to be a valuable contribution to the existing modes of testosterone treatment, combining therapeutic efficacy, convenience and safety.
Authors: Milou Cecilia Madsen; Martin den Heijer; Claudia Pees; Nienke R Biermasz; Leontine E H Bakker Journal: Endocr Connect Date: 2022-07-25 Impact factor: 3.221