Literature DB >> 19236037

Rhodium(I)-catalyzed cyclization reaction of o-alkynyl phenols and anilines. Domino approach to 2,3-disubstituted benzofurans and indoles.

Naohiro Isono1, Mark Lautens.   

Abstract

A rhodium-catalyzed cyclization of o-alkynylphenols and anilines followed by intermolecular conjugate addition that succeeds with alkyl and aryl alkynes is reported. In this reaction, 2,3-disubstituted benzofurans or indoles are obtained in one pot in good to excellent yields.

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Year:  2009        PMID： 19236037     DOI： 10.1021/ol9001174

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  A cycloisomerization/Friedel-Crafts alkylation strategy for the synthesis of pyrano[3,4-b]indoles.

Authors:  Matthew R Medeiros; Scott E Schaus; John A Porco
Journal:  Org Lett       Date:  2011-07-08       Impact factor: 6.005

2.  Exploring the potential of diarylacetylenediols as hydrogen bonding catalysts.

Authors:  Yunus E Türkmen; Viresh H Rawal
Journal:  J Org Chem       Date:  2013-08-14       Impact factor: 4.354

3.  Transition-metal-free base catalyzed intramolecular cyclization of 2-ynylphenols for efficient and facile synthesis of 2-substituted benzo[b]furans.

Authors:  Yong Liu; Tao Lu; Wei-Fang Tang; Jian Gao
Journal:  RSC Adv       Date:  2018-08-10       Impact factor: 3.361

4.  Palladium-Catalyzed Synthesis of 2,3-Disubstituted Benzofurans: An Approach Towards the Synthesis of Deuterium Labeled Compounds.

Authors:  Soumitra Agasti; Soham Maity; Kalman J Szabo; Debabrata Maiti
Journal:  Adv Synth Catal       Date:  2015-07-14       Impact factor: 5.837

5.  Synthesis and Application of 1,2-Aminoalcohols with Neoisopulegol-Based Octahydrobenzofuran Core.

Authors:  Fatima Zahra Bamou; Tam Minh Le; Bettina Volford; András Szekeres; Zsolt Szakonyi
Journal:  Molecules       Date:  2019-12-19       Impact factor: 4.411
  5 in total

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