Literature DB >> 1923533

Polymorphism at codon 213 within the p53 gene.

D Carbone1, I Chiba, T Mitsudomi.   

Abstract

This report describes a rare polymorphism at codon 213 (silent alteration of CGA to CGG) within the coding region of the p53 gene. The rare polymorphic allele was present in six cases out of 189 lung and breast cancer DNAs analyzed (3.2%) and resulted in the loss of a TaqI site. This allele could be mistaken for a mutation when screening methods of mutation analysis are used without comparison with normal tissue DNA.

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Year:  1991        PMID： 1923533

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  33 in total

1.  p53 gene alterations and protein accumulation in colorectal cancer.

Authors:  R Bertorelle; G Esposito; C Belluco; L Bonaldi; A Del Mistro; D Nitti; M Lise; L Chieco-Bianchi
Journal:  Clin Mol Pathol       Date:  1996-04

2.  p53 gene mutations in multiple myeloma.

Authors:  R G Owen; S A Davis; J Randerson; A C Rawstron; F Davies; J A Child; A S Jack; G J Morgan
Journal:  Mol Pathol       Date:  1997-02

3.  Specific p53 immunostaining patterns are associated with smoking habits in patients with oral squamous cell carcinomas.

Authors:  I Cruz; P J F Snijders; V Van Houten; M Vosjan; I Van der Waal; C J L M Meijer
Journal:  J Clin Pathol       Date:  2002-11       Impact factor: 3.411

4.  p53 mutations and expression in breast carcinoma in situ.

Authors:  J Lukas; N Niu; M F Press
Journal:  Am J Pathol       Date:  2000-01       Impact factor: 4.307

5.  Single base pair germ-line deletion in the p53 gene in a cancer predisposed family.

Authors:  R Hamelin; F Barichard; I Henry; C Junien; G Thomas
Journal:  Hum Genet       Date:  1994-07       Impact factor: 4.132

6.  Germline p53 mutations are frequently detected in young children with rhabdomyosarcoma.

Authors:  L Diller; E Sexsmith; A Gottlieb; F P Li; D Malkin
Journal:  J Clin Invest       Date:  1995-04       Impact factor: 14.808

7.  Pancreatic adenocarcinomas frequently show p53 gene mutations.

Authors:  A Scarpa; P Capelli; K Mukai; G Zamboni; T Oda; C Iacono; S Hirohashi
Journal:  Am J Pathol       Date:  1993-05       Impact factor: 4.307

8.  Lack of prognostic impact of p53 gene mutation and p53 phosphorylation at serine 15 in multimodally treated adenocarcinomas of the gastroesophageal junction.

Authors:  Franziska Pühringer-Oppermann; Michael Stahl; Gisela Keller; Mario Sarbia
Journal:  J Cancer Res Clin Oncol       Date:  2006-03-15       Impact factor: 4.553

9.  p53 gene mutations and MDM2 amplification are uncommon in primary carcinomas of the uterine cervix.

Authors:  T D Kessis; R J Slebos; S M Han; K Shah; X F Bosch; N Muñoz; L Hedrick; K R Cho
Journal:  Am J Pathol       Date:  1993-11       Impact factor: 4.307

10.  Functional studies of a germ-line polymorphism at codon 47 within the p53 gene.

Authors:  E Felley-Bosco; A Weston; H M Cawley; W P Bennett; C C Harris
Journal:  Am J Hum Genet       Date:  1993-09       Impact factor: 11.025
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