Literature DB >> 19235019

A new gliotoxin analogue from a marine-derived fungus Aspergillus fumigatus Fres.

Wen Ying Zhao1, Tian Jiao Zhu, Xiao Xian Han, Guo Tao Fan, Hong Bing Liu, Wei Ming Zhu, Qian Qun Gu.   

Abstract

A new gliotoxin analogue (1), as well as four known compounds gliotoxin (2), bisdethiobis (methylthio) gliotoxin (3), bis-N-norgliovictin (4) and didehydrobisdethiobis (methylthio) gliotoxin (5), were isolated from a culture of marine-derived fungus Aspergillus fumigatus Fres. The structure of 1 was determined on the basis of spectroscopic methods. All five compounds were evaluated for the cytotoxic effects on tsFT210 cell line by the SRB method.

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Year:  2009        PMID： 19235019     DOI： 10.1080/14786410600906970

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  6 in total

1.  Identification of cryptic products of the gliotoxin gene cluster using NMR-based comparative metabolomics and a model for gliotoxin biosynthesis.

Authors:  Ry R Forseth; Ellen M Fox; DaWoon Chung; Barbara J Howlett; Nancy P Keller; Frank C Schroeder
Journal:  J Am Chem Soc       Date:  2011-06-06       Impact factor: 15.419

2.  Exploring the chemodiversity and biological activities of the secondary metabolites from the marine fungus Neosartorya pseudofischeri.

Authors:  Wan-Ling Liang; Xiu Le; Hou-Jin Li; Xiang-Ling Yang; Jun-Xiong Chen; Jun Xu; Huan-Liang Liu; Lai-You Wang; Kun-Teng Wang; Kun-Chao Hu; De-Po Yang; Wen-Jian Lan
Journal:  Mar Drugs       Date:  2014-11-24       Impact factor: 5.118

Review 3.  An update on 2,5-diketopiperazines from marine organisms.

Authors:  Ri-Ming Huang; Xiang-Xi Yi; Yuying Zhou; Xiangdong Su; Yan Peng; Cheng-Hai Gao
Journal:  Mar Drugs       Date:  2014-12-19       Impact factor: 5.118

Review 4.  Structural Diversity and Biological Activities of the Cyclodipeptides from Fungi.

Authors:  Xiaohan Wang; Yuying Li; Xuping Zhang; Daowan Lai; Ligang Zhou
Journal:  Molecules       Date:  2017-11-23       Impact factor: 4.411

Review 5.  Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold.

Authors:  Joanna Bojarska; Adam Mieczkowski; Zyta M Ziora; Mariusz Skwarczynski; Istvan Toth; Ahmed O Shalash; Keykavous Parang; Shaima A El-Mowafi; Eman H M Mohammed; Sherif Elnagdy; Maha AlKhazindar; Wojciech M Wolf
Journal:  Biomolecules       Date:  2021-10-14

6.  Dichotocejpins A-C: New Diketopiperazines from a Deep-Sea-Derived Fungus Dichotomomyces cejpii FS110.

Authors:  Zhen Fan; Zhang-Hua Sun; Zhong Liu; Yu-Chan Chen; Hong-Xin Liu; Hao-Hua Li; Wei-Min Zhang
Journal:  Mar Drugs       Date:  2016-09-09       Impact factor: 5.118
  6 in total

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