Literature DB >> 19234138

Type I natural killer T cells suppress tumors caused by p53 loss in mice.

Jeremy B Swann1, Adam P Uldrich, Serani van Dommelen, Janelle Sharkey, William K Murray, Dale I Godfrey, Mark J Smyth.   

Abstract

CD1d-restricted T cells are considered to play a host protective effect in tumor immunity, yet the evidence for a role of natural killer T (NKT) cells in tumor immune surveillance has been weak and data from several tumor models has suggested that some (type II) CD1d-restricted T cells may also suppress some types of antitumor immune response. To substantiate an important role for CD1d-restricted T cells in host response to cancer, we have evaluated tumor development in p53(+/-) mice lacking either type I NKT cells (TCR Jalpha18(-/-)) or all CD1d-restricted T cells (CD1d(-/-)). Our findings support a key role for type I NKT cells in suppressing the onset of sarcomas and hematopoietic cancers caused by p53 loss but do not suggest that other CD1d-restricted T cells are critical in regulating the same tumor development.

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Year:  2009        PMID： 19234138      PMCID： PMC2710930          DOI： 10.1182/blood-2009-01-198564

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  26 in total

1.  NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma.

Authors:  M J Smyth; N Y Crowe; D I Godfrey
Journal:  Int Immunol       Date:  2001-04       Impact factor: 4.823

2.  NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway.

Authors:  M Terabe; S Matsui; N Noben-Trauth; H Chen; C Watson; D D Donaldson; D P Carbone; W E Paul; J A Berzofsky
Journal:  Nat Immunol       Date:  2000-12       Impact factor: 25.606

3.  Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFN-gamma dependent.

Authors:  Suzanne Ostrand-Rosenberg; Virginia K Clements; Masaki Terabe; Jong Myun Park; Jay A Berzofsky; Samudra K Dissanayake
Journal:  J Immunol       Date:  2002-11-15       Impact factor: 5.422

4.  Germline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer risk.

Authors:  Shih-Jen Hwang; Guillermina Lozano; Christopher I Amos; Louise C Strong
Journal:  Am J Hum Genet       Date:  2003-02-27       Impact factor: 11.025

5.  Alpha-galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis.

Authors:  Yoshihiro Hayakawa; Stefania Rovero; Guido Forni; Mark J Smyth
Journal:  Proc Natl Acad Sci U S A       Date:  2003-07-16       Impact factor: 11.205

6.  Absence of the CD1 molecule up-regulates antitumor activity induced by CpG oligodeoxynucleotides in mice.

Authors:  Lucia Sfondrini; Dario Besusso; Maria Teresa Zoia; Monica Rodolfo; Anna Maria Invernizzi; Masaru Taniguchi; Toshinori Nakayama; Mario Paolo Colombo; Sylvie Ménard; Andrea Balsari
Journal:  J Immunol       Date:  2002-07-01       Impact factor: 5.422

7.  Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma.

Authors:  M J Smyth; K Y Thia; S E Street; D MacGregor; D I Godfrey; J A Trapani
Journal:  J Exp Med       Date:  2000-09-04       Impact factor: 14.307

8.  A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas.

Authors:  Nadine Y Crowe; Mark J Smyth; Dale I Godfrey
Journal:  J Exp Med       Date:  2002-07-01       Impact factor: 14.307

9.  Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.

Authors:  Masaki Terabe; So Matsui; Jong-Myun Park; Mizuko Mamura; Nancy Noben-Trauth; Debra D Donaldson; Wanjun Chen; Sharon M Wahl; Steven Ledbetter; Bruce Pratt; John J Letterio; William E Paul; Jay A Berzofsky
Journal:  J Exp Med       Date:  2003-12-01       Impact factor: 14.307

10.  A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma.

Authors:  Madhav V Dhodapkar; Matthew D Geller; David H Chang; Kanako Shimizu; Shin-Ichiro Fujii; Kavita M Dhodapkar; Joseph Krasovsky
Journal:  J Exp Med       Date:  2003-06-09       Impact factor: 14.307
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  55 in total

Review 1.  Immunity, inflammation, and cancer.

Authors:  Sergei I Grivennikov; Florian R Greten; Michael Karin
Journal:  Cell       Date:  2010-03-19       Impact factor: 41.582

Review 2.  Lipid antigens in immunity.

Authors:  C Marie Dowds; Sabin-Christin Kornell; Richard S Blumberg; Sebastian Zeissig
Journal:  Biol Chem       Date:  2014-01       Impact factor: 3.915

3.  iNKT cell cytotoxic responses control T-lymphoma growth in vitro and in vivo .

Authors:  Hamid Bassiri; Rupali Das; Peng Guan; David M Barrett; Patrick J Brennan; Pinaki P Banerjee; Susan J Wiener; Jordan S Orange; Michael B Brenner; Stephan A Grupp; Kim E Nichols
Journal:  Cancer Immunol Res       Date:  2014-01       Impact factor: 11.151

Review 4.  Raising the roof: the preferential pharmacological stimulation of Th1 and th2 responses mediated by NKT cells.

Authors:  James E East; Andrew J Kennedy; Tonya J Webb
Journal:  Med Res Rev       Date:  2012-12-13       Impact factor: 12.944

5.  Immunosurveillance and immunoediting in MMTV-PyMT-induced mammary oncogenesis.

Authors:  Emilie T E Gross; Semi Han; Prasantha Vemu; Carlos D Peinado; Martin Marsala; Lesley G Ellies; Jack D Bui
Journal:  Oncoimmunology       Date:  2016-12-14       Impact factor: 8.110

6.  B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models.

Authors:  Changbin Shi; Robert Shenkar; Hussein A Zeineddine; Romuald Girard; Maged D Fam; Cecilia Austin; Thomas Moore; Rhonda Lightle; Lingjiao Zhang; Meijing Wu; Ying Cao; Murat Gunel; Angeliki Louvi; Autumn Rorrer; Carol Gallione; Douglas A Marchuk; Issam A Awad
Journal:  J Neuroimmune Pharmacol       Date:  2016-04-16       Impact factor: 4.147

Review 7.  Targeting natural killer cells and natural killer T cells in cancer.

Authors:  Eric Vivier; Sophie Ugolini; Didier Blaise; Christian Chabannon; Laurent Brossay
Journal:  Nat Rev Immunol       Date:  2012-03-22       Impact factor: 53.106

Review 8.  Innate and adaptive immune cells in the tumor microenvironment.

Authors:  Thomas F Gajewski; Hans Schreiber; Yang-Xin Fu
Journal:  Nat Immunol       Date:  2013-10       Impact factor: 25.606

Review 9.  Oncogenic stress sensed by the immune system: role of natural killer cell receptors.

Authors:  David H Raulet; Nadia Guerra
Journal:  Nat Rev Immunol       Date:  2009-08       Impact factor: 53.106

10.  Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation.

Authors:  Maya Kansara; Huei San Leong; Dan Mei Lin; Sophie Popkiss; Puiyi Pang; Dale W Garsed; Carl R Walkley; Carleen Cullinane; Jason Ellul; Nicole M Haynes; Rod Hicks; Marieke L Kuijjer; Anne-Marie Cleton-Jansen; Philip W Hinds; Mark J Smyth; David M Thomas
Journal:  J Clin Invest       Date:  2013-11-15       Impact factor: 14.808
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