| Literature DB >> 19233606 |
Jean-Marc Trocello1, Philippe Chappuis, Pascal Chaine, Pascal Rémy, Dominique Debray, Jean-Charles Duclos-Vallée, France Woimant.
Abstract
UNLABELLED: Wilson Disease must be considered in very varied circumstances, including in patients older than 50 years. Its diagnosis is not based on a single test but on a group of findings. The copper levels may be difficult to interpret. Molecular biology can confirm the diagnosis in only 80% of cases. The advice of the reference center is necessary before beginning treatment: chelators or zinc salts. Lifetime treatment is required. Follow-up of these patients must be regular and multidisciplinary and should be conducted in association with the reference center. Inclusion in the national registry for Wilson Disease must be suggested to all patients. CONTACT: cmr.wilson@lrb.aphp.fr.Entities:
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Year: 2009 PMID: 19233606 DOI: 10.1016/j.lpm.2008.11.017
Source DB: PubMed Journal: Presse Med ISSN: 0755-4982 Impact factor: 1.228