Literature DB >> 19232208

[Evaluation and maintenance of the lung donor].

Francisco Del Río1, Dolores Escudero, Braulio De La Calle, Federico Gordo Vidal, María Valentín Paredes, José Ramón Núñez.   

Abstract

Spain has a rate of 34.4 donors per million population, making it the country with the highest rate of organ donation all over the world. In spite of these values, need of lungs for transplantation is always greater than the number of organs obtained. The adrenergic storming produced during brain herniation and the initiation of a brain death condition entail a series of pathophysiological alterations that can endanger the lung viability. In this paper, we review the evaluation of lung donor and its maintenance. In all the potential lung donors, the Apnea Test with CPAP should be done and the criteria for the donation of the lung under ideal conditions and with expanded criteria lung donors are reviewed. The protocol of aggressive maintenance including a protective ventilation strategy, restricted fluid intake, use of prophylactic antibiotics, corticosteroids and the systematic use of measures aimed at avoiding alveolar collapse together with maneuvers aimed at achieving better lung recruitment can improve the management of the lung donor and obtain a greater number of organs for transplantation.

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Year:  2009        PMID: 19232208     DOI: 10.1016/s0210-5691(09)70304-3

Source DB:  PubMed          Journal:  Med Intensiva        ISSN: 0210-5691            Impact factor:   2.491


  3 in total

1.  Boussignac CPAP system for brain death confirmation with apneic test in case of acute lung injury/adult respiratory distress syndrome - series of cases.

Authors:  Andrzej Wieczorek; Tomasz Gaszynski
Journal:  Ther Clin Risk Manag       Date:  2015-06-17       Impact factor: 2.423

2.  Lung donation and donor lung management: a survey among health care professionals in Argentina.

Authors:  Vanesa Romina Ruiz; Sergio Adrián Terrasa; Susana Bauque; Pablo Ezequiel Rodriguez; Verónica Celia Morozovsky; Alejandro Gabriel Da Lozzo; Alejandro Daniel Midley
Journal:  Rev Bras Ter Intensiva       Date:  2022-01-24

3.  Impact of implementing a protocol of respiratory care measures and optimization of mechanical ventilation in potential lung donors.

Authors:  Marco Guillermo Bezzi; Carla Candela Brovia; Juan Manuel Carballo; Maia Inés Elías; Agustina Belén Moreno; Vanesa Romina Ruiz; Fernanda Cordiviola; David Barbieri; Adriana Fariña; Silvina Borello
Journal:  Rev Bras Ter Intensiva       Date:  2020 Oct-Dec
  3 in total

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