| Literature DB >> 19231593 |
Carine Blanchard1, Marc E Rothenberg.
Abstract
In this review, we aim to put in perspective the biology of a multifunctional leukocyte, the eosinophil, by placing it in the context of innate and adaptive immune responses. Eosinophils have a unique contribution in initiating inflammatory and adaptive responses, due to their bidirectional interactions with dendritic cells and T cells, as well as their large panel of secreted cytokines and soluble mediators. The mechanisms and consequences of eosinophil responses in experimental inflammatory models and human diseases are discussed.Entities:
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Year: 2009 PMID: 19231593 PMCID: PMC4109275 DOI: 10.1016/S0065-2776(08)01003-1
Source DB: PubMed Journal: Adv Immunol ISSN: 0065-2776 Impact factor: 3.543