Literature DB >> 19230972

Inhibition of all-trans retinoic acid-induced granulocytic differentiation of WEHI-3B D+ cells by forced expression of SCL (TAL1) and GATA-1.

Kimiko Ishiguro1, Anna M Rice, Kevin P Rice, Alan C Sartorelli.   

Abstract

All-trans retinoic acid (ATRA) induces granulocytic maturation of WEHI-3B D+ leukemia cells and LiCl enhances this maturation, while WEHI-3B D- cells are non-responsive to ATRA. Transfection of SCL, expressed in D- but absent in D+ cells, into D+ cells, caused resistance to ATRA, while transfection of GATA-1 into D+ cells produced resistance to the combination of ATRA and LiCl. SCL expression in D+ cells did not induce the expression of c-Kit, a putative target gene for SCL. LiCl, known to inhibit some kinases by displacing Mg2+, did not affect tyrosine kinase activity of the cytoplasmic domain of c-Kit.

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Year:  2009        PMID： 19230972      PMCID： PMC2780339          DOI： 10.1016/j.leukres.2009.01.022

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  42 in total

Review 1.  The stem cell leukaemia (SCL) gene: a critical regulator of haemopoietic and vascular development.

Authors:  L M Barton; B Göttgens; A R Green
Journal:  Int J Biochem Cell Biol       Date:  1999-10       Impact factor: 5.085

Review 2.  Hematopoietic cytokines, transcription factors and lineage commitment.

Authors:  Jiang Zhu; Stephen G Emerson
Journal:  Oncogene       Date:  2002-05-13       Impact factor: 9.867

3.  Lyn is required for normal stem cell factor-induced proliferation and chemotaxis of primary hematopoietic cells.

Authors:  B O'Laughlin-Bunner; N Radosevic; M L Taylor; C DeBerry; D D Metcalfe; M Zhou; C Lowell; D Linnekin
Journal:  Blood       Date:  2001-07-15       Impact factor: 22.113

4.  Lithium inhibits glycogen synthase kinase-3 by competition for magnesium.

Authors:  W J Ryves; A J Harwood
Journal:  Biochem Biophys Res Commun       Date:  2001-01-26       Impact factor: 3.575

Review 5.  Molecular targets of lithium action.

Authors:  C J Phiel; P S Klein
Journal:  Annu Rev Pharmacol Toxicol       Date:  2001       Impact factor: 13.820

6.  The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1.

Authors:  Eric Lécuyer; Sabine Herblot; Marianne Saint-Denis; Richard Martin; C Glenn Begley; Catherine Porcher; Stuart H Orkin; Trang Hoang
Journal:  Blood       Date:  2002-10-01       Impact factor: 22.113

7.  Analysis of the relationship between Scl transcription factor complex protein expression patterns and the effects of LiCl on ATRA-induced differentiation in blast cells from patients with acute myeloid leukemia.

Authors:  Anna M Rice; Kathleen M Holtz; Judith Karp; Sandra Rollins; Alan C Sartorelli
Journal:  Leuk Res       Date:  2004-11       Impact factor: 3.156

8.  Combination of all-trans retinoic acid and lithium chloride surmounts a retinoid differentiation block induced by expression of Scl and Rbtn2 transcription factors in myeloid leukemia cells.

Authors:  Anna M Rice; Jianming Li; Alan C Sartorelli
Journal:  Leuk Res       Date:  2004-04       Impact factor: 3.156

9.  A phase I study of bexarotene, a retinoic X receptor agonist, in non-M3 acute myeloid leukemia.

Authors:  Donald E Tsai; Selina M Luger; Charalambos Andreadis; Dan T Vogl; Allison Kemner; Melissa Potuzak; Ami Goradia; Alison W Loren; Alexander E Perl; Stephen J Schuster; David L Porter; Edward A Stadtmauer; Steven C Goldstein; James E Thompson; Cezary Swider; Adam Bagg; Anthony R Mato; Martin Carroll
Journal:  Clin Cancer Res       Date:  2008-09-01       Impact factor: 12.531

10.  Activation of transiently transfected reporter genes in 3T3 Swiss cells by the inducers of differentiation/apoptosis--dimethylsulfoxide, hexamethylene bisacetamide and trichostatin A.

Authors:  Kimiko Ishiguro; Alan C Sartorelli
Journal:  Eur J Biochem       Date:  2004-06
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