Literature DB >> 1922973

An in vitro model to study diabetic neuropathy.

J R Sotelo1, H Horie, S Ito, C Benech, K Sango, T Takenaka.   

Abstract

Adult dorsal root ganglion (DRG) neurons from diabetic and normal C57BL mice were cultured and compared for survival and neurite extension. Neurons from diabetic mice have improved their survival and neurite extension when the insulin concentration was increased but it was never as good as that of controls. The increase of glucose concentration in serum-free media to ten times higher than normal improved both survival and neurite extension of neurons from diabetic animals.

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Year:  1991        PMID: 1922973     DOI: 10.1016/0304-3940(91)90727-b

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  5 in total

1.  Dorsal Root Ganglia Sensory Neuronal Cultures: a tool for drug discovery for peripheral neuropathies.

Authors:  Giorgia Melli; Ahmet Höke
Journal:  Expert Opin Drug Discov       Date:  2009-10-01       Impact factor: 6.098

2.  A brief review of in vitro models of diabetic neuropathy.

Authors:  Namita G Hattangady; Medha S Rajadhyaksha
Journal:  Int J Diabetes Dev Ctries       Date:  2009-10

3.  Eosinophils increase neuron branching in human and murine skin and in vitro.

Authors:  Erin L Foster; Eric L Simpson; Lorna J Fredrikson; James J Lee; Nancy A Lee; Allison D Fryer; David B Jacoby
Journal:  PLoS One       Date:  2011-07-21       Impact factor: 3.240

Review 4.  Impaired Axonal Regeneration in Diabetes. Perspective on the Underlying Mechanism from In Vivo and In Vitro Experimental Studies.

Authors:  Kazunori Sango; Hiroki Mizukami; Hidenori Horie; Soroku Yagihashi
Journal:  Front Endocrinol (Lausanne)       Date:  2017-02-01       Impact factor: 5.555

5.  Therapeutic Potential of Dioscorea Extract (DA-9801) in Comparison with Alpha Lipoic Acid on the Peripheral Nerves in Experimental Diabetes.

Authors:  Heung Yong Jin; Sun Hee Kim; Hea Min Yu; Hong Sun Baek; Tae Sun Park
Journal:  J Diabetes Res       Date:  2013-03-12       Impact factor: 4.011

  5 in total

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