Literature DB >> 19229132

roX RNAs: non-coding regulators of the male X chromosome in flies.

Ibrahim Ilik1, Asifa Akhtar.   

Abstract

The roX RNAs represent one of the paradigm examples of large non-coding RNAs involved in chromatin regulation. Interestingly, roX genes have a dual life. The RNA product is part of the MSL complex required for dosage compensation of the male X chromosome in Drosophila while the genomic location is used as a binding platform for MSL complex assembly. In this review we discuss both aspects of roX function and propose an integrated model for possible mechanisms how these RNAs might be involved in epigenetic regulation of the male X chromosome.

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Year:  2009        PMID: 19229132     DOI: 10.4161/rna.6.2.8060

Source DB:  PubMed          Journal:  RNA Biol        ISSN: 1547-6286            Impact factor:   4.652


  20 in total

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Authors:  Lingjie Li; Howard Y Chang
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2.  RNA splicing control: yet another gene regulatory role for long nuclear noncoding RNAs.

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Review 3.  Non-coding RNAs in chromatin folding and nuclear organization.

Authors:  Sergey V Razin; Alexey A Gavrilov
Journal:  Cell Mol Life Sci       Date:  2021-06-11       Impact factor: 9.261

Review 4.  The chromatin signaling pathway: diverse mechanisms of recruitment of histone-modifying enzymes and varied biological outcomes.

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Journal:  Mol Cell       Date:  2010-12-10       Impact factor: 17.970

Review 5.  Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts.

Authors:  Marco Magistri; Mohammad Ali Faghihi; Georges St Laurent; Claes Wahlestedt
Journal:  Trends Genet       Date:  2012-04-26       Impact factor: 11.639

6.  Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila.

Authors:  Ibrahim Avsar Ilik; Jeffrey J Quinn; Plamen Georgiev; Filipe Tavares-Cadete; Daniel Maticzka; Sarah Toscano; Yue Wan; Robert C Spitale; Nicholas Luscombe; Rolf Backofen; Howard Y Chang; Asifa Akhtar
Journal:  Mol Cell       Date:  2013-07-25       Impact factor: 17.970

Review 7.  RNA structure probing uncovers RNA structure-dependent biological functions.

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Journal:  Nat Chem Biol       Date:  2021-06-25       Impact factor: 15.040

Review 8.  Advancing our understanding of functional genome organisation through studies in the fission yeast.

Authors:  Ida Olsson; Pernilla Bjerling
Journal:  Curr Genet       Date:  2010-11-27       Impact factor: 3.886

9.  msl2 mRNA is bound by free nuclear MSL complex in Drosophila melanogaster.

Authors:  Anna-Mia Johansson; Anders Allgardsson; Per Stenberg; Jan Larsson
Journal:  Nucleic Acids Res       Date:  2011-05-06       Impact factor: 16.971

10.  The novel long non-coding RNA CRG regulates Drosophila locomotor behavior.

Authors:  Meixia Li; Shengyun Wen; Xiangqian Guo; Baoyan Bai; Zhefeng Gong; Xiaojun Liu; Yijin Wang; Yanqiong Zhou; Xiaowei Chen; Li Liu; Runsheng Chen
Journal:  Nucleic Acids Res       Date:  2012-10-15       Impact factor: 16.971

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