Literature DB >> 19228208

Histopathological profile of surgically removed persistent periapical radiolucent lesions of endodontic origin.

R M Love1, N Firth.   

Abstract

AIM: To determine the types of periapical lesions associated with root filled teeth with persistent periapical pathosis that required surgical treatment based on specific inclusion and exclusion criteria.
METHODOLOGY: Periapical lesions from a consecutive clinical sample of 100 patients were examined histopathologically to determine a definitive diagnosis.
RESULTS: Females were more represented (n = 56), the average age was 46.5 years and there were no age differences between gender or lesion type. A diagnosis of periapical granuloma was the most common finding with a similar number present in females (n = 40) and males (n = 37). A cyst was present in 18% of the cases with a majority of females (n = 12) represented in the sample. Evidence of foreign material, with an appearance consistent with endodontic sealer materials, was seen in 25 periapical granulomas, two cysts and one scar. Two periapical scars were seen, one had a history of apicectomy and amalgam root-end filling while the other was associated with extruded root filling material.
CONCLUSIONS: By using defined clinical inclusion and exclusion criteria a predictable clinical diagnosis of a persistent periapical lesion due to endodontic origin can be reliably made. Periapical granulomas and cysts were the most common periapical lesions of endodontic origin associated with persistent periapical pathosis with the overall incidence of periapical cysts similar to previous studies. The presence of endodontic material in a high proportion of periapical lesions suggests a cause-effect association with the inference that clinicians should employ canal preparation techniques that limit apical extrusion of material.

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Year:  2009        PMID: 19228208     DOI: 10.1111/j.1365-2591.2008.01500.x

Source DB:  PubMed          Journal:  Int Endod J        ISSN: 0143-2885            Impact factor:   5.264


  10 in total

Review 1.  Association between diabetes and the prevalence of radiolucent periapical lesions in root-filled teeth: systematic review and meta-analysis.

Authors:  Juan J Segura-Egea; Jenifer Martín-González; Daniel Cabanillas-Balsera; Ashraf F Fouad; Eugenio Velasco-Ortega; José López-López
Journal:  Clin Oral Investig       Date:  2016-04-08       Impact factor: 3.573

2.  Long-term outcome of non-surgical root canal treatment: a retrospective analysis.

Authors:  Chiara Pirani; Stefano Chersoni; Lucio Montebugnoli; Carlo Prati
Journal:  Odontology       Date:  2014-06-08       Impact factor: 2.634

Review 3.  Endodontic Periapical Lesion: An Overview on the Etiology, Diagnosis and Current Treatment Modalities.

Authors:  Kasra Karamifar; Afsoon Tondari; Mohammad Ali Saghiri
Journal:  Eur Endod J       Date:  2020-07-14

4.  Decompression of a Large Periapical Lesion: A Case Report of 4-Year Follow-Up.

Authors:  Claudio Maniglia-Ferreira; Fabio de Almeida Gomes; Marcelo de Morais Vitoriano; Francisco de Assis Silva Lima
Journal:  Case Rep Med       Date:  2016-12-12

5.  Differential diagnosis of periapical cyst using collagen birefringence pattern of the cyst wall.

Authors:  Hyo Jin Ji; Se-Hee Park; Kyung-Mo Cho; Suk Keun Lee; Jin Woo Kim
Journal:  Restor Dent Endod       Date:  2017-02-09

6.  Clinical and radiological analysis of a series of periapical cysts and periapical granulomas diagnosed in a Brazilian population.

Authors:  Daniel-Petitet Tavares; Janderson-Teixeira Rodrigues; Teresa-Cristina-Ribeiro-Bartholomeu Dos Santos; Luciana Armada; Fábio-Ramôa Pires
Journal:  J Clin Exp Dent       Date:  2017-01-01

7.  Evaluation of concordance between clinical and histopathological diagnoses in periapical lesions of endodontic origin.

Authors:  Ohoud Alotaibi; Sara Alswayyed; Rana Alshagroud; Manal AlSheddi
Journal:  J Dent Sci       Date:  2020-04-18       Impact factor: 2.080

8.  Inflammatory cell expression of Toll-like receptor-2 (TLR2) within refractory periapical granuloma.

Authors:  Eric Chen; Mahmoud M Bakr; Norman Firth; Robert M Love
Journal:  F1000Res       Date:  2018-11-20

9.  Non-endodontic periapical lesions clinically diagnosed as endodontic periapical lesions: A retrospective study over 15 years.

Authors:  Theerachai Kosanwat; Sopee Poomsawat; Jira Kitisubkanchana
Journal:  J Clin Exp Dent       Date:  2021-06-01

10.  Endodontic Management of Open Apex Teeth Using Lyophilized Collagen Sponge and MTA Cement: Report of Two Cases.

Authors:  Miriam Graziele Magro; Milton Carlos Kuga; Weber Adad Ricci; Kátia Cristina Keine; Mateus Rodrigues Tonetto; Suellen Linares Lima; Alvaro Henrique Borges; Lauriê Garcia Belizário; Matheus Coêlho Bandeca
Journal:  Iran Endod J       Date:  2017
  10 in total

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