Literature DB >> 19225929

"Burned out" testicular seminoma presenting as a primary gastric malignancy.

Hector Mesa1, Ajay Rawal, Anthony Rezcallah, Carlos Iwamoto, Gloria A Niehans, Paul Druck, Pankaj Gupta.   

Abstract

In contrast to primary gastric adenocarcinomas, germ cell tumors are potentially curable even when metastatic. It is therefore essential for clinicians and pathologists to be aware of the spectrum of unusual manifestations of germ cell malignancies. Here we report on a 55-year-old man who presented with clinical and endoscopic features indicative of a primary gastric carcinoma. Surprisingly, the ulcerative mucosal lesion was found to be due to a metastasis from an occult, "burned-out" testicular seminoma. This case describes the radiological and pathological features that helped differentiate this rare situation from the much more common gastric adenocarcinoma, and extends the diagnostic possibilities that must be considered in patients presenting with gastric ulcers.

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Year:  2009        PMID: 19225929     DOI: 10.1007/s10147-008-0804-0

Source DB:  PubMed          Journal:  Int J Clin Oncol        ISSN: 1341-9625            Impact factor:   3.402


  26 in total

1.  In search of an unknown primary tumour presenting with extracervical metastases: the diagnostic performance of FDG-PET.

Authors:  U Joshi; J J M van der Hoeven; E F I Comans; G J Herder; G J J Teule; O S Hoekstra
Journal:  Br J Radiol       Date:  2004-12       Impact factor: 3.039

2.  Hematogenous metastases to the stomach. A review of 67 cases.

Authors:  L K Green
Journal:  Cancer       Date:  1990-04-01       Impact factor: 6.860

3.  Diagnostic value of markers M2A, OCT3/4, AP-2gamma, PLAP and c-KIT in the detection of extragonadal seminomas.

Authors:  K Biermann; D Klingmüller; A Koch; T Pietsch; H Schorle; R Büttner; H Zhou
Journal:  Histopathology       Date:  2006-09       Impact factor: 5.087

4.  Cisplatin, etoposide and either bleomycin or ifosfamide in the treatment of disseminated germ cell tumors: final analysis of an intergroup trial.

Authors:  Stuart Hinton; Paul J Catalano; Lawrence H Einhorn; Craig R Nichols; E David Crawford; Nicholas Vogelzang; Donald Trump; Patrick J Loehrer
Journal:  Cancer       Date:  2003-04-15       Impact factor: 6.860

5.  [Spontaneously involuting metastatic seminoma of the testis ("burned-out seminoma"). Report of a case presenting with supraclavicular adenopathy].

Authors:  O Weber; J Hubert; Y Grignon; P Mangin
Journal:  Prog Urol       Date:  1996-04       Impact factor: 0.915

6.  "Bull's-eye" lesions. Solitary or multiple nodules in the gastrointestinal tract with large central ulceration.

Authors:  M M Reeder; R C Cavanagh
Journal:  JAMA       Date:  1974-08-12       Impact factor: 56.272

7.  Unusual and late metastases from seminomas.

Authors:  O V Nielsen; S P Jorgensen; F Koch
Journal:  Acta Chir Scand       Date:  1972

8.  ["Burned out" testicular tumor: a rare form of germ cell neoplasias].

Authors:  R Casella; C Rochlitz; G Sauter; T C Gasser
Journal:  Schweiz Med Wochenschr       Date:  1999-02-13

9.  Endoscopic appearance of cancer metastatic to the stomach.

Authors:  R S Sandler; R B Sartor; E M Bozymski
Journal:  J Clin Gastroenterol       Date:  1981       Impact factor: 3.062

10.  [Extragonadal germ cell tumor with "burned-out" phenomenon in the testis].

Authors:  A Ojea Calvo; A Rodríguez Alonso; D Pérez García; F Domínguez Freire; A Alonso Rodrigo; B Rodríguez Iglesias; J Benavente Delgado; J M Barros Rodríguez; C Fiaño Valverde; J L Nogueira March
Journal:  Actas Urol Esp       Date:  1999 Nov-Dec       Impact factor: 0.994

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  6 in total

1.  Gastric metastases from testicular cancer: case report and review of literature.

Authors:  Salvatore Lauro; Riccardo Righini; Concetta Elisa Onesti; Eugenio Pucci; Alessandra Bramini; Paolo Marchetti
Journal:  J Gastrointest Cancer       Date:  2014-12

2.  'Prechronous' metastasis in clear cell renal cell carcinoma: a case report.

Authors:  Eileen Poon; Sin Jen Ong; Xue En Chuang; Wan Teck Lim; Nor Azhari Mohd Zam; Tsung Wen Chong; Issam Al Jajeh; Kent Mancer; Min-Han Tan
Journal:  J Med Case Rep       Date:  2011-05-13

Review 3.  Beyond gastric adenocarcinoma: Multimodality assessment of common and uncommon gastric neoplasms.

Authors:  Danielle M Richman; Sree Harsha Tirumani; Jason L Hornick; Charles S Fuchs; Stephanie Howard; Katherine Krajewski; Nikhil Ramaiya; Michael Rosenthal
Journal:  Abdom Radiol (NY)       Date:  2017-01

4.  Gastric recurrence of a primary colon plasmacytoma: staging and evaluating response to therapy with 18F-FDG PET/CT.

Authors:  W Makis; A Ciarallo; M Hickeson; R Lisbona
Journal:  Br J Radiol       Date:  2012-01       Impact factor: 3.039

5.  Seminoma presenting as a solitary metastasis in gastric mucosa with regressed testicular mass.

Authors:  Ren Yuan; Chen Zhou; Victor Meneghetti; Jean-Michel Lavoie; Christian Kollmannsberger; Gang Wang
Journal:  Urol Case Rep       Date:  2019-12-03

6.  Brain Metastases as Presenting Feature in 'Burned Out' Testicular Germ Cell Tumor.

Authors:  Kate Johnson; Bryan Brunet
Journal:  Cureus       Date:  2016-04-01
  6 in total

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