Literature DB >> 19223786

Normal versus high tension glaucoma: a comparison of functional and structural defects.

Oraorn Thonginnetra1, Vivienne C Greenstein, David Chu, Jeffrey M Liebmann, Robert Ritch, Donald C Hood.   

Abstract

PURPOSE: To compare visual field defects obtained with both multifocal visual evoked potential (mfVEP) and Humphrey visual field (HVF) techniques to topographic optic disc measurements in patients with normal tension glaucoma (NTG) and high tension glaucoma (HTG).
METHODS: We studied 32 patients with NTG and 32 with HTG. All patients had reliable 24-2 HVFs with a mean deviation of -10 dB or better, a glaucomatous optic disc and an abnormal HVF in at least 1 eye. Multifocal VEPs were obtained from each eye and probability plots created. The mfVEP and HVF probability plots were divided into a central 10-degree radius and an outer arcuate subfield in both superior and inferior hemifields. Cluster analyses and counts of abnormal points were performed in each subfield. Optic disc images were obtained with the Heidelberg Retina Tomograph III. Eleven stereometric parameters were calculated. Moorfields regression analysis and the glaucoma probability score were performed.
RESULTS: There were no significant differences in mean deviation and pattern standard deviation values between NTG and HTG eyes. However, NTG eyes had a higher percentage of abnormal test points and clusters of abnormal points in the central subfields on both mfVEP and HVF than HTG eyes. For Heidelberg Retina Tomograph III, there were no significant differences in the 11 stereometric parameters or in the Moorfields regression analysis and glaucoma probability score analyses of the optic disc images.
CONCLUSIONS: The visual field data suggest more localized and central defects for NTG than HTG.

Entities:  

Mesh:

Year:  2010        PMID: 19223786      PMCID: PMC2891909          DOI: 10.1097/IJG.0b013e318193c45c

Source DB:  PubMed          Journal:  J Glaucoma        ISSN: 1057-0829            Impact factor:   2.503


  41 in total

Review 1.  Multifocal VEP and ganglion cell damage: applications and limitations for the study of glaucoma.

Authors:  Donald C Hood; Vivienne C Greenstein
Journal:  Prog Retin Eye Res       Date:  2003-03       Impact factor: 21.198

2.  Quantifying the benefits of additional channels of multifocal VEP recording.

Authors:  Donald C Hood; Xian Zhang; Jenny E Hong; Candice S Chen
Journal:  Doc Ophthalmol       Date:  2002-05       Impact factor: 2.379

3.  A signal-to-noise analysis of multifocal VEP responses: an objective definition for poor records.

Authors:  Xian Zhang; Donald C Hood; Candice S Chen; Jenny E Hong
Journal:  Doc Ophthalmol       Date:  2002-05       Impact factor: 2.379

4.  Detecting early to mild glaucomatous damage: a comparison of the multifocal VEP and automated perimetry.

Authors:  Donald C Hood; Phamornsak Thienprasiddhi; Vivienne C Greenstein; Bryan J Winn; Nitin Ohri; Jeffrey M Liebmann; Robert Ritch
Journal:  Invest Ophthalmol Vis Sci       Date:  2004-02       Impact factor: 4.799

5.  Multifocal visual evoked potential responses in glaucoma patients with unilateral hemifield defects.

Authors:  Phamornsak Thienprasiddhi; Vivienne C Greenstein; Candice S Chen; Jeffrey M Liebmann; Robert Ritch; Donald C Hood
Journal:  Am J Ophthalmol       Date:  2003-07       Impact factor: 5.258

6.  Objective VEP perimetry in glaucoma: asymmetry analysis to identify early deficits.

Authors:  S L Graham; A I Klistorner; J R Grigg; F A Billson
Journal:  J Glaucoma       Date:  2000-02       Impact factor: 2.503

7.  A comparison of optic disc topographic parameters in patients with primary open angle glaucoma, normal tension glaucoma, and ocular hypertension.

Authors:  Naoko Kiriyama; Akira Ando; Chieko Fukui; Hiroyuki Nambu; Maki Nishikawa; Hiroo Terauchi; Atsuko Kuwahara; Miyo Matsumura
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2003-06-18       Impact factor: 3.117

8.  Detecting glaucomatous damage with multifocal visual evoked potentials: how can a monocular test work?

Authors:  Donald C Hood; Xian Zhang; Bryan J Winn
Journal:  J Glaucoma       Date:  2003-02       Impact factor: 2.503

9.  Exploring the Heidelberg Retinal Tomograph 3 diagnostic accuracy across disc sizes and glaucoma stages: a multicenter study.

Authors:  Francesco Oddone; Marco Centofanti; Luca Rossetti; Michele Iester; Paolo Fogagnolo; Elisabetta Capris; Gianluca Manni
Journal:  Ophthalmology       Date:  2008-03-05       Impact factor: 12.079

Review 10.  The impact of ocular blood flow in glaucoma.

Authors:  Josef Flammer; Selim Orgül; Vital P Costa; Nicola Orzalesi; Günter K Krieglstein; Luis Metzner Serra; Jean-Paul Renard; Einar Stefánsson
Journal:  Prog Retin Eye Res       Date:  2002-07       Impact factor: 21.198

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  24 in total

1.  Early glaucoma involves both deep local, and shallow widespread, retinal nerve fiber damage of the macular region.

Authors:  Donald C Hood; Anastasia Slobodnick; Ali S Raza; Carlos Gustavo de Moraes; Christopher C Teng; Robert Ritch
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-02-03       Impact factor: 4.799

2.  Clinical use of multifocal visual-evoked potentials in a glaucoma practice: a prospective study.

Authors:  Carlos Gustavo De Moraes; Jeffrey M Liebmann; Robert Ritch; Donald C Hood
Journal:  Doc Ophthalmol       Date:  2012-04-05       Impact factor: 2.379

3.  Vertical Macular Asymmetry Measures Derived From SD-OCT for Detection of Early Glaucoma.

Authors:  Farideh Sharifipour; Esteban Morales; Ji Woong Lee; JoAnn Giaconi; Abdelmonem A Afifi; Fei Yu; Joseph Caprioli; Kouros Nouri-Mahdavi
Journal:  Invest Ophthalmol Vis Sci       Date:  2017-08-01       Impact factor: 4.799

4.  Initial central scotomas vs peripheral scotomas in normal-tension glaucoma: clinical characteristics and progression rates.

Authors:  H-K Cho; J Lee; M Lee; C Kee
Journal:  Eye (Lond)       Date:  2013-12-20       Impact factor: 3.775

5.  Structural changes of macular inner retinal layers in early normal-tension and high-tension glaucoma by spectral-domain optical coherence tomography.

Authors:  Florian S M Edlinger; Laura M Schrems-Hoesl; Christian Y Mardin; Robert Laemmer; Friedrich E Kruse; Wolfgang A Schrems
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2018-03-09       Impact factor: 3.117

6.  Intraocular retinal thickness asymmetry in early stage of primary open angle glaucoma and normal tension glaucoma.

Authors:  Pei-Wen Lin; Hsueh-Wen Chang; Ing-Chou Lai; Jen-Chia Tsai; Yi-Chieh Poon
Journal:  Int J Ophthalmol       Date:  2018-08-18       Impact factor: 1.779

7.  Predicting the risk of parafoveal scotoma in myopic normal tension glaucoma: role of optic disc tilt and rotation.

Authors:  M S Sung; H Heo; Y S Ji; S W Park
Journal:  Eye (Lond)       Date:  2017-03-10       Impact factor: 3.775

Review 8.  Normal tension glaucoma: review of current understanding and mechanisms of the pathogenesis.

Authors:  H E Killer; A Pircher
Journal:  Eye (Lond)       Date:  2018-02-19       Impact factor: 3.775

9.  Neuroprotection of rat retinal ganglion cells mediated through alpha7 nicotinic acetylcholine receptors.

Authors:  K Iwamoto; D Mata; D M Linn; C L Linn
Journal:  Neuroscience       Date:  2013-02-10       Impact factor: 3.590

10.  Relationship between disc margin to fovea distance and central visual field defect in normal tension glaucoma.

Authors:  Marvin Lee; Hosung Jin; Jaehong Ahn
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2013-11-22       Impact factor: 3.117

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