Literature DB >> 19223381

The expression and clinical significance of TGF-beta1 and MMP2 in human renal clear cell carcinoma.

Shu-Dong Yang1, Rong-Chao Sun, Hui-Jun Mu, Zhuo-Qun Xu, Zhi-Yi Zhou.   

Abstract

The expression and clinical significance of transforming growth factor beta1 (TGF-beta1) and matrix metalloproteinase-2 (MMP2) in human renal clear cell carcinoma (RCCC) were investigated. The intensity of TGF-beta1 and MMP2 expression in RCCC kidneys was significantly higher than that in normal kidneys. Expression of TGF-beta1 and MMP2 in RCCC tissues was positively correlated with pathological grade and clinical stage. There was also a significant correlation between TGF-beta1 and Msshese analyses indicate that upregulation of TGF-beta1 and MMP2 expression may occur during the progression of RCCC. Thus, TGF-beta1 and MMP2 may be useful molecular markers for evaluating prognosis in RCCC patients.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19223381     DOI： 10.1177/1066896909331993

Source DB:  PubMed          Journal:  Int J Surg Pathol        ISSN： 1066-8969            Impact factor:   1.271


  6 in total

1.  Antitumor activity of irradiated riboflavin on human renal carcinoma cell line 786-O.

Authors:  Antonio Hernandes Chaves Neto; Karin Juliane Pelizzaro-Rocha; Maruska Neufert Fernandes; Carmen Veríssima Ferreira-Halder
Journal:  Tumour Biol       Date:  2014-10-02

2.  Fibronectin Promotes Cell Growth and Migration in Human Renal Cell Carcinoma Cells.

Authors:  Yen-Chuan Ou; Jian-Ri Li; Jiaan-Der Wang; Cheng-Yi Chang; Chih-Cheng Wu; Wen-Ying Chen; Yu-Hsiang Kuan; Su-Lan Liao; Hsi-Chi Lu; Chun-Jung Chen
Journal:  Int J Mol Sci       Date:  2019-06-07       Impact factor: 5.923

3.  G6PD upregulates Cyclin E1 and MMP9 to promote clear cell renal cell carcinoma progression.

Authors:  Qiao Zhang; Yueli Ni; Shujie Wang; Yannick Luther Agbana; Qiaoqiao Han; Wenjing Liu; Honggang Bai; Zihan Yi; Xiaojia Yi; Yuzhi Zhu; Buqing Sai; Lijuan Yang; Qiong Shi; Yingmin Kuang; Zhe Yang; Yuechun Zhu
Journal:  Int J Med Sci       Date:  2022-01-01       Impact factor: 3.738

4.  Jagged-1 is induced by mTOR inhibitors in renal cancer cells through an Akt/ALK5/Smad4-dependent mechanism.

Authors:  David Danielpour; Sarah Corum; Patrick Leahy; Anusha Bangalore
Journal:  Curr Res Pharmacol Drug Discov       Date:  2022-07-04

5.  The expression and clinical significance of matrix metalloproteinase 7 and tissue inhibitor of matrix metalloproteinases 2 in clear cell renal cell carcinoma.

Authors:  Hongsheng Lu; Zhaohui Yang; Hui Zhang; Meifu Gan; Tao Zhou; Siling Wang
Journal:  Exp Ther Med       Date:  2012-12-17       Impact factor: 2.447

Review 6.  Mechanistic basis and clinical relevance of the role of transforming growth factor-β in cancer.

Authors:  Run-Long Lin; Lu-Jun Zhao
Journal:  Cancer Biol Med       Date:  2015-12       Impact factor: 4.248
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.