BACKGROUND: Percutaneous vertebroplasty appears beneficial for patients with acute compression fractures of multiple aetiologies including myeloma, osteoporosis and trauma. There are few reports on its use in the setting of metastatic solid malignancy. METHODS: We identified all individuals who had undergone percutaneous vertebroplasty at our institution since 2004 and focused on those with metastatic solid malignancies. Their clinical characteristics and outcomes were investigated. RESULTS: From 136 cases that underwent percutaneous vertebroplasties, 19 were performed mainly in breast, prostate, lung and renal cancers. Of these 19 cases, 10 patients (53%) were treated for solitary lesions, 3 (16%) were injected at two levels and the remaining 6 cases (31%) underwent cement injection at three levels. The majority of individuals (84%) reported short- and long-term symptomatic improvements. At a median follow-up of one year, six patients have died. CONCLUSIONS: Percutaneous vertebroplasty appears as an effective palliative procedure in patients with compression fractures secondary to metastatic solid malignancy. Its use can be successfully combined with other treatment modalities (radiotherapy and chemotherapy).
BACKGROUND: Percutaneous vertebroplasty appears beneficial for patients with acute compression fractures of multiple aetiologies including myeloma, osteoporosis and trauma. There are few reports on its use in the setting of metastatic solid malignancy. METHODS: We identified all individuals who had undergone percutaneous vertebroplasty at our institution since 2004 and focused on those with metastatic solid malignancies. Their clinical characteristics and outcomes were investigated. RESULTS: From 136 cases that underwent percutaneous vertebroplasties, 19 were performed mainly in breast, prostate, lung and renal cancers. Of these 19 cases, 10 patients (53%) were treated for solitary lesions, 3 (16%) were injected at two levels and the remaining 6 cases (31%) underwent cement injection at three levels. The majority of individuals (84%) reported short- and long-term symptomatic improvements. At a median follow-up of one year, six patients have died. CONCLUSIONS: Percutaneous vertebroplasty appears as an effective palliative procedure in patients with compression fractures secondary to metastatic solid malignancy. Its use can be successfully combined with other treatment modalities (radiotherapy and chemotherapy).
Authors: Ning Mao Kam; Julian Maingard; Hong Kuan Kok; Dinesh Ranatunga; Duncan Brooks; William C Torreggiani; Peter L Munk; Michael J Lee; Ronil V Chandra; Hamed Asadi Journal: Curr Treat Options Oncol Date: 2017-11-16
Authors: Flavio Tancioni; Martin Lorenzetti; Pierina Navarria; Andrea Nozza; Luca Castagna; Paolo Gaetani; Enrico Aimar; Daniel Levi; Antonio Di Ieva; Patrizia Pisano; Armando Santoro; Marta Scorsetti; Riccardo Rodriguez y Baena Journal: Neurol Sci Date: 2010-04 Impact factor: 3.307