Literature DB >> 19222491

New and emerging treatments for osteoporosis.

Bart L Clarke1.   

Abstract

A variety of new treatments for osteoporosis have become available within the last several years, and a number of emerging treatments remain in late clinical stage development. New and emerging treatments include more potent members, or more convenient formulations, of existing classes of therapy, but a number of the emerging treatments are first-generation compounds addressing specific therapeutic targets based on recent advances in understanding of basic bone biology. These new and emerging treatments include agents with anticatabolic effects, compounds with anabolic effects, and one agent possibly containing both anticatabolic and anabolic effects. The increasing variety of new and emerging treatments increases the possibility that effective therapy will be targeted to the specific needs of the individual patient.

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Year:  2009        PMID: 19222491     DOI: 10.1111/j.1365-2265.2009.03541.x

Source DB:  PubMed          Journal:  Clin Endocrinol (Oxf)        ISSN: 0300-0664            Impact factor:   3.478


  2 in total

1.  Bortezomib prevents ovariectomy-induced osteoporosis in mice by inhibiting osteoclast differentiation.

Authors:  Sung-Hyun Kim; Myoung Ok Kim; Hyo Jeong Kim; Sanjiv Neupane; Hyung Joon Kim; Ji Hye Lee; Hong-Hee Kim; Jae-Young Kim; Youngkyun Lee
Journal:  J Bone Miner Metab       Date:  2017-10-12       Impact factor: 2.626

2.  Efficacy and Safety of Denosumab in Osteoporosis or Low Bone Mineral Density Postmenopausal Women.

Authors:  Yi Chen; Jun Zhu; Yiqin Zhou; Jinhui Peng; Bo Wang
Journal:  Front Pharmacol       Date:  2021-04-14       Impact factor: 5.810

  2 in total

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