Literature DB >> 19220244

Impact of body mass index on clinical and cost outcomes after radical cystectomy.

Aditya Bagrodia1, Sonal Grover, Abhishek Srivastava, Amit Gupta, Christian Bolenz, Arthur I Sagalowsky, Yair Lotan.   

Abstract

OBJECTIVE: To evaluate the effect of body mass index (BMI, kg/m(2)) on the cost and clinical variables after radical cystectomy (RC), as studies show that obesity might adversely affect the outcomes after RC. PATIENTS AND METHODS: The charts of patients who had RC from January 2004 to March 2007 were reviewed retrospectively. Complete cost and clinical information was available for 99 patients; the patient and tumour characteristics and peri-operative outcomes were recorded. Detailed cost information (room and board, laboratory, pharmacy, radiology, operating room, surgical supply, anaesthesia, and recovery room) was obtained from hospital billing. Patients were stratified and compared in three groups of BMI, i.e. normal weight (<25), overweight (25-<30) and obese (> or =30).
RESULTS: The mean age of the patients was 66 years; 27% were normal weight, 38% were overweight and 34% were obese. Of obese patients, 24% had an Eastern Cooperative Oncology Group performance score of 0, vs none and 2.6% in the normal and overweight groups, respectively (P = 0.001). Those of normal weight had the highest overall and major complication rates (P = 0.57 and 0.28, respectively). Obese patients had insignificantly higher transfusion rates (P = 0.28). The direct cost was higher in normal weight ($14,314) than overweight ($13,808) and obese ($13,666) patients (P = 0.47). Higher room and board cost in normal-weight patients was the only significant cost difference (P = 0.008).
CONCLUSION: BMI was not associated with increased costs of cystectomy. The absence of differences in cost-related and clinical outcomes might be attributable to variable comorbidity among groups and the experience of a high-volume surgeon and staff at a tertiary-care referral centre that routinely cares for obese patients.

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Year:  2009        PMID: 19220244     DOI: 10.1111/j.1464-410X.2009.08358.x

Source DB:  PubMed          Journal:  BJU Int        ISSN: 1464-4096            Impact factor:   5.588


  5 in total

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Authors:  Ana P Johnson; Joel L Parlow; Brian Milne; Marlo Whitehead; Jianfeng Xu; Susan Rohland; Joelle B Thorpe
Journal:  Eur J Health Econ       Date:  2016-05-11

2.  Mortality after radical cystectomy: impact of obesity versus adiposity after adjusting for skeletal muscle wasting.

Authors:  Sarah P Psutka; Stephen A Boorjian; Michael R Moynagh; Grant D Schmit; Igor Frank; Alonso Carrasco; Suzanne B Stewart; Robert Tarrell; Prabin Thapa; Matthew K Tollefson
Journal:  J Urol       Date:  2014-11-22       Impact factor: 7.450

Review 3.  [Influence of obesity on urological malignancies].

Authors:  H Eggers; M A Kuczyk; A J Schrader; S Steffens
Journal:  Urologe A       Date:  2013-09       Impact factor: 0.639

4.  Impact of preoperative body mass index on perioperative outcomes is optimized by enhanced recovery protocols in laparoscopic radical cystectomy with intracorporeal urinary diversion.

Authors:  Houyi Wei; Jiandong Gao; Mingshuai Wang; Wahafu Wasilijiang; Pan Ai; Xiaoguang Zhou; Liyan Cui; Liming Song; Anshi Wu; Nianzeng Xing; Yinong Niu
Journal:  Transl Androl Urol       Date:  2021-05

5.  Patterns of care in patients with muscle-invasive bladder cancer - a retrospective cohort study.

Authors:  Sławomir Poletajew; Radosław Biernacki; Paweł Buraczyński; Jarosław Chojnacki; Stefan Czarniecki; Dominika Gajewska; Tomasz Pohaba; Joanna Sondka; Michał Skrzypczyk; Tomasz Suchojad; Dominik Wojtkowiak; Bogusław Zaforemski; Łukasz Zapała; Aleksandra Zemła; Piotr Radziszewski
Journal:  Contemp Oncol (Pozn)       Date:  2016-09-05
  5 in total

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