| Literature DB >> 19219867 |
Dominique Amans1, Véronique Bellosta, Janine Cossy.
Abstract
Concise and highly convergent syntheses of the immunosuppressive agent FR252921 and the related antimicrobial natural product pseudotrienic acid B were achieved from a common intermediate by using optically active titanium complexes to control the configuration of the stereogenic centers, a highly stereo- and regioselective cross-metathesis to generate the triene moieties, and a Stille cross-coupling to install the dienic units.Entities:
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Year: 2009 PMID： 19219867 DOI： 10.1002/chem.200802649
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236