Literature DB >> 19219735

A new cytotoxic homoisoflavonoid from Dracaena cambodiana.

Jian Liu1, Wen-Li Mei, Jiao Wu, You-Xing Zhao, Ming Peng, Hao-Fu Dai.   

Abstract

A new homoisoflavonoid, named cambodianol (1), together with the two known flavanes, (2S)-7,3'-dihydroxy-4'-methoxy-8-methylflavane (2) and (2R)-7,4'-dihydroxy-8-methylflavane (3), were isolated from the stems of Dracaena cambodiana. Their structures were determined based on HR-ESI-MS and spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 1 exhibited significant cytotoxic activities against K562 and SGC-7901 with the IC(50) values of 1.4 and 2.9 microg/ml, respectively.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19219735     DOI： 10.1080/10286020802674962

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN： 1028-6020            Impact factor:   1.569


  4 in total

Review 1.  Flavonoids and Stilbenoids of the Genera Dracaena and Sansevieria: Structures and Bioactivities.

Authors:  Zaw Min Thu; Ko Ko Myo; Hnin Thanda Aung; Chabaco Armijos; Giovanni Vidari
Journal:  Molecules       Date:  2020-06-03       Impact factor: 4.411

2.  Antioxidant phenolic compounds of Dracaena cambodiana.

Authors:  Ying Luo; Hui Wang; Xuerong Xu; Wenli Mei; Haofu Dai
Journal:  Molecules       Date:  2010-12-06       Impact factor: 4.411

3.  HM-Chromanone Isolated from Portulaca oleracea L. Protects INS-1 Pancreatic β Cells against Glucotoxicity-Induced Apoptosis.

Authors:  Jae Eun Park; Youngwan Seo; Ji Sook Han
Journal:  Nutrients       Date:  2019-02-14       Impact factor: 5.717

Review 4.  A Comprehensive Review on Chemotaxonomic and Phytochemical Aspects of Homoisoflavonoids, as Rare Flavonoid Derivatives.

Authors:  Javad Mottaghipisheh; Hermann Stuppner
Journal:  Int J Mol Sci       Date:  2021-03-08       Impact factor: 5.923
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.