BACKGROUND: Gallstone formation is one of the most common complications after gastric cancer surgery, but the mechanism and etiology for such formation are unclear because of a lack of collective clinical investigation. METHOD: We evaluated the influence of various surgical factors on the incidence of gallstone formation after gastrectomy. Gallstone formation was confirmed by ultrasound examinations that were routinely carried out after surgery on a periodic basis. RESULTS: Gallstone formation occurred in 173 of 672 (25.7%) patients who had undergone gastrectomy with lymph-node dissection for gastric cancer. The types of gastrectomy and reconstruction had no significant effect on the incidence, but the extent of lymph-node dissection was a significant factor (p < 0.001: D1 + alpha vs. D2 + alpha; p < 0.01: D2 vs. D2 + alpha). Gallstones were usually formed within 2 years after gastrectomy, but in most cases, gallstone formation was asymptomatic. CONCLUSION: The extent of lymph-node dissection was a significant factor in gallstone formation after gastrectomy; therefore, prophylactic cholecystectomy should be considered in cases of extensive lymph-node dissection.
BACKGROUND:Gallstone formation is one of the most common complications after gastric cancer surgery, but the mechanism and etiology for such formation are unclear because of a lack of collective clinical investigation. METHOD: We evaluated the influence of various surgical factors on the incidence of gallstone formation after gastrectomy. Gallstone formation was confirmed by ultrasound examinations that were routinely carried out after surgery on a periodic basis. RESULTS:Gallstone formation occurred in 173 of 672 (25.7%) patients who had undergone gastrectomy with lymph-node dissection for gastric cancer. The types of gastrectomy and reconstruction had no significant effect on the incidence, but the extent of lymph-node dissection was a significant factor (p < 0.001: D1 + alpha vs. D2 + alpha; p < 0.01: D2 vs. D2 + alpha). Gallstones were usually formed within 2 years after gastrectomy, but in most cases, gallstone formation was asymptomatic. CONCLUSION: The extent of lymph-node dissection was a significant factor in gallstone formation after gastrectomy; therefore, prophylactic cholecystectomy should be considered in cases of extensive lymph-node dissection.
Authors: Bernabé M Quesada; Gustavo Kohan; Hernán E Roff; Carlos M Canullán; Luis T Chiappetta Porras Journal: World J Gastroenterol Date: 2010-05-07 Impact factor: 5.742
Authors: Marco Bernini; Lapo Bencini; Riccardo Sacchetti; Alberto Marchet; Luigi Cristadoro; Fabio Pacelli; Stefano Berardi; Giovanni B Doglietto; Fausto Rosa; Giuseppe Verlato; Luca Cozzaglio; Paolo Bechi; Daniele Marrelli; Franco Roviello; Marco Farsi Journal: Gastric Cancer Date: 2012-09-05 Impact factor: 7.370
Authors: You Na Kim; Ji Yeong An; Min-Gew Choi; Jun Ho Lee; Tae Sung Sohn; Jae Moon Bae; Sung Kim Journal: Chin J Cancer Res Date: 2019-06 Impact factor: 5.087