Literature DB >> 19217841

[Adult Schönlein-Henoch purpura associated with epidermoid carcinoma of the lung].

Makram Frigui1, Manel Kechaou, Mohamed Ben Hmida, Khaoula Kamoun, Afef Khanfir, Mounir Frikha, Jamil Hachicha, Zouhir Bahloul.   

Abstract

INTRODUCTION: Association between Schönlein-Henoch purpura and neoplasm can suggest the responsibility of tumour antigens in the genesis of the vasculitis. We report a new case of squamous cell carcinoma associated with Schönlein-Henoch purpura and we discuss the reality of this association. CASE REPORT: We report the case of a 50-year-old man who presents Schönlein-Henoch purpura with a purpura of lower limbs, joint involvement, gastrointestinal lesions and IgA renal mesangial deposits. The patient received three intravenous methylprednisolone pulses followed with oral corticosteroids. Six months later, while the vasculitis was in remission, the patient presented a squamous cell lung carcinoma. He was treated by chemotherapy and local radiotherapy. At the late follow-up, the neoplasm was incompletely resolved.
CONCLUSION: The neoplasm could be responsible of the development of the Schönlein-Henoch purpura. The discovery of this systemic vasculitis in an elderly patient should warrant a deep screening for an occult neoplasm.

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Year:  2009        PMID: 19217841     DOI: 10.1016/j.nephro.2008.11.001

Source DB:  PubMed          Journal:  Nephrol Ther        ISSN: 1769-7255            Impact factor:   0.722


  4 in total

1.  Henoch-Schönlein purpura associated with a neuroblastoma: Report of one case and a review of the literature.

Authors:  Qiaoli Dong; Shanshan Cao; Hongwen Zhang; Hui Geng
Journal:  Intractable Rare Dis Res       Date:  2012-11

2.  Adult Henoch-Schönlein purpura associated with small cell lung cancer: A case report and review of the literature.

Authors:  Xue-DE Zhang; Shuan-Ying Yang; Wei Li; Zong-Juan Ming; Yan-Li Hou; Ze-Qun Niu; Yu-Ping Zhang
Journal:  Oncol Lett       Date:  2013-03-27       Impact factor: 2.967

3.  Henoch Schönlein purpura associated with pulmonary adenocarcinoma.

Authors:  Daiki Mifune; Satoshi Watanabe; Rie Kondo; Yoko Wada; Hiroshi Moriyama; Hiroshi Kagamu; Hirohisa Yoshizawa; Takafumi Tetsuka; Asako Matsuyama; Kaoru Ito; Ichiei Narita
Journal:  J Med Case Rep       Date:  2011-06-22

4.  The spectrum of paraneoplastic cutaneous vasculitis in a defined population: incidence and clinical features.

Authors:  Javier Loricera; Vanesa Calvo-Río; Francisco Ortiz-Sanjuán; Marcos A González-López; Hector Fernández-Llaca; Javier Rueda-Gotor; Maria C Gonzalez-Vela; Lino Alvarez; Cristina Mata; Domingo González-Lamuño; Victor M Martínez-Taboada; Miguel A González-Gay; Ricardo Blanco
Journal:  Medicine (Baltimore)       Date:  2013-11       Impact factor: 1.889

  4 in total

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