| Literature DB >> 19217417 |
Michela Noseda, Michael D Schneider.
Abstract
Within the developing and adult heart, the fibroblast is often dismissed as merely a structural element, important just to mechanical integrity or to scarring when excessive in disease. Ieda et al. in this issue of Developmental Cell now report an essential program of paracrine factor production in cardiac fibroblasts that controls heart muscle cell growth, driving cycling or enlargement depending on the fibroblasts' developmental stage.Mesh:
Substances:
Year: 2009 PMID: 19217417 DOI: 10.1016/j.devcel.2009.01.020
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270