Literature DB >> 19216305

Awake thyroidectomy under local anesthesia and dexmedetomidine infusion.

Anthony R Plunkett1, Cynthia Shields, Alex Stojadinovic, Chester C Buckenmaier.   

Abstract

UNLABELLED: Dexmedetomidine (DEX) is an alpha-2 receptor agonist with sedative and analgesic properties. It has been reported to preserve the patient's ability to cooperate and provide opioid sparing properties. Patients with obstructive sleep apnea (OSA) have demonstrated an increased risk for oxygen desaturation following general anesthesia. We report a case of a 64-year-old male, ASA IV with severe chronic obstructive pulmonary disease, OSA, unilateral vocal cord dysfunction, gastro-esophageal reflux disease, and congestive heart failure undergoing an awake thyroidectomy under local anesthesia and a DEX infusion. The patient was given a loading dose of DEX of 1 mcg/kg and an infusion ranging from 0.2 to 1.0 g/kg/hr. He received a total of 250 mcg of fentanyl and 7.5 mg of ketorolac throughout the case.
RESULTS: The patient tolerated the procedure well. He was able to cooperate with simple commands. His vital signs remained stable. He reported a pain score of 2 out of 10 in the recovery unit.
CONCLUSIONS: This case demonstrates the successful use of a DEX infusion along with local anesthesia administered by the surgeon for an awake thyroidectomy.

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Year:  2009        PMID: 19216305     DOI: 10.7205/milmed-d-01-2908

Source DB:  PubMed          Journal:  Mil Med        ISSN: 0026-4075            Impact factor:   1.437


  3 in total

1.  Update on dexmedetomidine: use in nonintubated patients requiring sedation for surgical procedures.

Authors:  Mohanad Shukry; Jeffrey A Miller
Journal:  Ther Clin Risk Manag       Date:  2010-04-15       Impact factor: 2.423

2.  A systematic review of the effects of sedatives and anesthetics in patients with obstructive sleep apnea.

Authors:  Saravanan Ankichetty; Jean Wong; Frances Chung
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2011-10

3.  Effect of Dexmedetomidine on Perioperative Stress Response and Immune Function in Patients With Tumors.

Authors:  Lihong Zheng; Juan Zhao; Likun Zheng; Shuangfeng Jing; Xiaoting Wang
Journal:  Technol Cancer Res Treat       Date:  2020 Jan-Dec
  3 in total

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