Literature DB >> 19216084

Improved results of the vacuum assisted closure and Nitinol clips sternal closure after postoperative deep sternal wound infection.

Maria Pia Tocco1, Alberto Costantino, Milva Ballardini, Claudio D'Andrea, Marcello Masala, Eusebio Merico, Luigi Mosillo, Paolo Sordini.   

Abstract

OBJECTIVE: Postoperative deep sternal wound infection is a severe complication of cardiac surgery, with a high mortality rate and a high morbidity rate. The objective of this prospective study is to report our experience with the vacuum assisted closure (VAC) system for the management of deep wound infection. We also devised an innovative closure technique post VAC therapy using thermo reactive clips. The advantage of this technique is that the posterior face of the sternum does not have to be separated from the mediastinal structures thus minimising the risk of damage.
METHODS: From October 2006 to October 2008, we prospectively evaluated 21 patients affected by mediastinitis after sternotomy. Nineteen patients had sternotomy for coronary artery bypass grafting (CABG), one patient for aortic valve replacement (AVR) and another one for ascending aortic replacement (AAR). All patients were treated with the VAC system at the time of infection diagnosis. When the wound tissue appeared viable and the microbiological cultures were negative, the chest was closed using the most suitable procedure for the patient in question; nine patients were closed using pectoralis flaps, nine patients using Nitinol clips, one patient with a combined technique (use of Nitinol clips and muscle flap), one patient with a direct wound closure and another patient, who needed AAR with a homograft performed in another institution, was closed using sternal wires.
RESULTS: We had no mortality; wound healing was successfully achieved in all patients. In more than 50% of the patients, the VAC therapy allowed direct sternal resynthesis. The average duration of the vacuum therapy was 26 days (range 14-37 days).
CONCLUSIONS: VAC is a safe and effective option in the treatment of post-sternotomy mediastinitis, with excellent survival and immediate improvement of local wound conditions; furthermore, the use of Nitinol clips after VAC therapy demonstrated to be a safe and non-invasive option for sternal resynthesis. After VAC therapy, a reduction in number of muscular flaps used and an increase of direct sternal resynthesis were observed.

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Year:  2009        PMID: 19216084     DOI: 10.1016/j.ejcts.2008.12.036

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  11 in total

1.  Candidal mediastinitis successfully treated using vacuum-assisted closure following open-heart surgery.

Authors:  Hiroaki Osada; Hiroyuki Nakajima; Manabu Morishima; Takamitsu Su
Journal:  Interact Cardiovasc Thorac Surg       Date:  2012-03-14

2.  The 'Two Bridges Technique' for sternal wound closure. The use of vacuum-assisted closure for the treatment of deep sternal wound defects: a centre-specific technique.

Authors:  Karl Waked; Philippe Ballaux; Dominique Goossens; Koen Cathenis
Journal:  Int Wound J       Date:  2018-02-12       Impact factor: 3.315

3.  Positive outcomes with negative pressure therapy over primarily closed large abdominal wall reconstruction reduces surgical site infection rates.

Authors:  A Gassman; A Mehta; E Bucholdz; A Abthani; O Guerra; M M Maclin; T Esposito; C Thomas
Journal:  Hernia       Date:  2014-10-22       Impact factor: 4.739

Review 4.  Infectious complications of cardiac surgery: a clinical review.

Authors:  Matthew E Cove; Denis W Spelman; Graeme MacLaren
Journal:  J Cardiothorac Vasc Anesth       Date:  2012-07-04       Impact factor: 2.628

5.  Platelet-rich plasma inside the sternotomy wound reduces the incidence of sternal wound infections.

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Review 7.  Poststernotomy mediastinitis: a classification to initiate and evaluate reconstructive management based on evidence from a structured review.

Authors:  Jan J van Wingerden; Dirk T Ubbink; Chantal M A M van der Horst; Bas A J M de Mol
Journal:  J Cardiothorac Surg       Date:  2014-11-23       Impact factor: 1.637

Review 8.  Prevention, Diagnosis and Management of Post-Surgical Mediastinitis in Adults Consensus Guidelines of the Spanish Society of Cardiovascular Infections (SEICAV), the Spanish Society of Thoracic and Cardiovascular Surgery (SECTCV) and the Biomedical Research Centre Network for Respiratory Diseases (CIBERES).

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Journal:  J Clin Med       Date:  2021-11-26       Impact factor: 4.241

9.  Vacuum assistance therapy as compared to early reconstructive treatment in deep sternal wound infection.

Authors:  E Hämäläinen; J Laurikka; H Huhtala; O Järvinen
Journal:  Scand J Surg       Date:  2020-12-16       Impact factor: 2.360

10.  Negative pressure wound therapy decreases mortality in a murine model of burn-wound sepsis involving Pseudomonas aeruginosa infection.

Authors:  Yang Liu; Qin Zhou; Yunchuan Wang; Zhengcai Liu; Maolong Dong; Yaojun Wang; Xiao Li; Dahai Hu
Journal:  PLoS One       Date:  2014-02-28       Impact factor: 3.240

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