Evidence-based dentistry and the concept of harm.

Evidence-based medicine requires the integration of best research evidence with the clinician's expertise and the patient's unique values and circumstances. One of the most important issues in deciding what course of treatment to select is balancing the potential risks and benefits of treatment. A framework for evidence-based decision-making includes formulating the clinical question and then retrieving, appraising, and considering the applicability of the evidence to the patient. It is the duty of all health care providers to reduce patient risk by selecting appropriate therapies and informing patients of unavoidable risks.