BACKGROUND: Although low back pain can be principally produced or increased during action, it may also be induced or enhanced in the morning after bed rest. During bed rest, tissue edema (increased water content) may occur. In this study, we measured the changes in water content in the intervertebral disc and the paravertebral muscle before and after bed rest using a magnetization transfer magnetic resonance imaging (MT-MRI) technique that permits measuring water content in tissues. METHODS: A total of 20 student volunteers were enrolled in this study. MT-MRI evaluation was performed before and after bed rest. To measure water content in the intervertebral disc and paravertebral muscle, two MRI sequences were performed using MT pulse-off and MT pulse-on. Based on the two images obtained, the equivalent cross-relaxation rate (ECR) was calculated. RESULTS: The ECR for intervertebral discs was significantly lower after bed rest than before bed rest (P < 0.01). The ECR for paravertebral equivalent cross-relaxation rate muscles was significantly higher after bed rest than before bed rest (P < 0.05). CONCLUSION: We obtained results indicating that after bed rest the water content in the intervertebral disc and the paravertebral muscle was increased and decreased, respectively.
BACKGROUND: Although low back pain can be principally produced or increased during action, it may also be induced or enhanced in the morning after bed rest. During bed rest, tissue edema (increased water content) may occur. In this study, we measured the changes in water content in the intervertebral disc and the paravertebral muscle before and after bed rest using a magnetization transfer magnetic resonance imaging (MT-MRI) technique that permits measuring water content in tissues. METHODS: A total of 20 student volunteers were enrolled in this study. MT-MRI evaluation was performed before and after bed rest. To measure water content in the intervertebral disc and paravertebral muscle, two MRI sequences were performed using MT pulse-off and MT pulse-on. Based on the two images obtained, the equivalent cross-relaxation rate (ECR) was calculated. RESULTS: The ECR for intervertebral discs was significantly lower after bed rest than before bed rest (P < 0.01). The ECR for paravertebral equivalent cross-relaxation rate muscles was significantly higher after bed rest than before bed rest (P < 0.05). CONCLUSION: We obtained results indicating that after bed rest the water content in the intervertebral disc and the paravertebral muscle was increased and decreased, respectively.
Authors: Daniel L Belavy; Michael Adams; Helena Brisby; Barbara Cagnie; Lieven Danneels; Jeremy Fairbank; Alan R Hargens; Stefan Judex; Richard A Scheuring; Roope Sovelius; Jill Urban; Jaap H van Dieën; Hans-Joachim Wilke Journal: Eur Spine J Date: 2015-04-18 Impact factor: 3.134
Authors: Britta Berg-Johansen; Ellen C Liebenberg; Alfred Li; Brandon R Macias; Alan R Hargens; Jeffrey C Lotz Journal: J Orthop Res Date: 2015-08-31 Impact factor: 3.494
Authors: M Kordi; D L Belavý; G Armbrecht; A Sheikh; D Felsenberg; G Trudel Journal: J Musculoskelet Neuronal Interact Date: 2015-09 Impact factor: 2.041
Authors: Cornelis P L Paul; Theodoor H Smit; Magda de Graaf; Roderick M Holewijn; Arno Bisschop; Peter M van de Ven; Margriet G Mullender; Marco N Helder; Gustav J Strijkers Journal: PLoS One Date: 2018-01-30 Impact factor: 3.240