Literature DB >> 19214320

Inhibition of selectin binding by colloidal gold with functionalized shells.

Jens Dernedde1, Sven Enders, Hans-Ulrich Reissig, Meike Roskamp, Sabine Schlecht, Shahla Yekta.   

Abstract

Gold colloids with terminally functionalized sulfated thiol shells were found to bind to P- and L-selectins with IC(50) values in the picomolar range; branched acyclic epitopes show the highest affinity, whereas a sulfated carbohydrate mimetic provides the best selectivity.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19214320     DOI： 10.1039/b818263a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Addition of lithiated enol ethers to nitrones and subsequent Lewis acid induced cyclizations to enantiopure 3,6-dihydro-2H-pyrans - an approach to carbohydrate mimetics.

Authors:  Fabian Pfrengle; Hans-Ulrich Reissig
Journal:  Beilstein J Org Chem       Date:  2010-07-09       Impact factor: 2.883

2.  Synthesis of multivalent carbohydrate mimetics with aminopolyol end groups and their evaluation as L-selectin inhibitors.

Authors:  Joana Salta; Jens Dernedde; Hans-Ulrich Reissig
Journal:  Beilstein J Org Chem       Date:  2015-05-05       Impact factor: 2.883

3.  Synthesis of new enantiopure poly(hydroxy)aminooxepanes as building blocks for multivalent carbohydrate mimetics.

Authors:  Léa Bouché; Maja Kandziora; Hans-Ulrich Reissig
Journal:  Beilstein J Org Chem       Date:  2014-01-20       Impact factor: 2.883

4.  Iodination of carbohydrate-derived 1,2-oxazines to enantiopure 5-iodo-3,6-dihydro-2H-1,2-oxazines and subsequent palladium-catalyzed cross-coupling reactions.

Authors:  Michal Medvecký; Igor Linder; Luise Schefzig; Hans-Ulrich Reissig; Reinhold Zimmer
Journal:  Beilstein J Org Chem       Date:  2016-12-29       Impact factor: 2.883

Review 5.  The engagement of selectins and their ligands in colorectal cancer liver metastases.

Authors:  Konstantinos A Paschos; David Canovas; Nigel C Bird
Journal:  J Cell Mol Med       Date:  2010-01       Impact factor: 5.310

6.  Synthesis of rigid p-terphenyl-linked carbohydrate mimetics.

Authors:  Maja Kandziora; Hans-Ulrich Reissig
Journal:  Beilstein J Org Chem       Date:  2014-07-30       Impact factor: 2.883
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.