Literature DB >> 19212271

Longitudinal changes in sexual functioning as women transition through menopause: results from the Study of Women's Health Across the Nation.

Nancy E Avis1, Sarah Brockwell, John F Randolph, Shunhua Shen, Virginia S Cain, Marcia Ory, Gail A Greendale.   

Abstract

OBJECTIVE: Sexual functioning is an important component of women's lives. The extent to which the menopausal transition is associated with decreased sexual functioning remains inconclusive. This study seeks to determine if advancing through the menopausal transition is associated with changes in sexual functioning.
METHODS: This was a prospective, longitudinal cohort study of women aged 42 to 52 years at baseline recruited at seven US sites (N = 3,302) in the Study of Women's Health Across the Nation (SWAN). Cohort-eligible women had an intact uterus, had at least one ovary, were not currently using exogenous hormones, were either premenopausal or early perimenopausal, and self-identified as one of the study's designated racial/ethnic groups. Data from the baseline interview and six annual follow-up visits are reported. Outcomes are self-reported ratings of importance of sex; frequency of sexual desire, arousal, masturbation, sexual intercourse, and pain during intercourse; and degree of emotional satisfaction and physical pleasure.
RESULTS: With adjustment for baseline age, chronological aging, and relevant social, health, and psychological parameters, the odds of reporting vaginal or pelvic pain increased and desire decreased by late perimenopause. Masturbation increased at early perimenopause but declined during postmenopause. The menopausal transition was unrelated to other outcomes. Health, psychological functioning, and importance of sex were related to all sexual function outcomes. Age, race/ethnicity, marital status, change in relationship, and vaginal dryness were also associated with sexual functioning.
CONCLUSIONS: Pain during sexual intercourse increases and sexual desire decreases over the menopausal transition. Masturbation increases during the early transition, but then declines in postmenopause. With adjustment for other factors, the menopausal transition was not independently associated with reports of the importance of sex, sexual arousal, frequency of sexual intercourse, emotional satisfaction with partner, or physical pleasure.

Entities:  

Mesh:

Year:  2009        PMID: 19212271      PMCID: PMC2908487          DOI: 10.1097/gme.0b013e3181948dd0

Source DB:  PubMed          Journal:  Menopause        ISSN: 1072-3714            Impact factor:   2.953


  43 in total

1.  The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function.

Authors:  R Rosen; C Brown; J Heiman; S Leiblum; C Meston; R Shabsigh; D Ferguson; R D'Agostino
Journal:  J Sex Marital Ther       Date:  2000 Apr-Jun

2.  Attitudes toward menopause and aging across ethnic/racial groups.

Authors:  B Sommer; N Avis; P Meyer; M Ory; T Madden; M Kagawa-Singer; C Mouton; N O Rasor; S Adler
Journal:  Psychosom Med       Date:  1999 Nov-Dec       Impact factor: 4.312

3.  Is there an association between menopause status and sexual functioning?

Authors:  N E Avis; R Stellato; S Crawford; C Johannes; C Longcope
Journal:  Menopause       Date:  2000 Sep-Oct       Impact factor: 2.953

4.  A data-based approach to diet questionnaire design and testing.

Authors:  G Block; A M Hartman; C M Dresser; M D Carroll; J Gannon; L Gardner
Journal:  Am J Epidemiol       Date:  1986-09       Impact factor: 4.897

5.  Comparative validation of the Block, Willett, and National Cancer Institute food frequency questionnaires : the Eating at America's Table Study.

Authors:  A F Subar; F E Thompson; V Kipnis; D Midthune; P Hurwitz; S McNutt; A McIntosh; S Rosenfeld
Journal:  Am J Epidemiol       Date:  2001-12-15       Impact factor: 4.897

6.  Epidemiology Standardization Project (American Thoracic Society).

Authors:  B G Ferris
Journal:  Am Rev Respir Dis       Date:  1978-12

Review 7.  Sexual function and aging in men and women: community and population-based studies.

Authors:  N E Avis
Journal:  J Gend Specif Med       Date:  2000 Mar-Apr

8.  Are changes in sexual functioning during midlife due to aging or menopause?

Authors:  L Dennerstein; E Dudley; H Burger
Journal:  Fertil Steril       Date:  2001-09       Impact factor: 7.329

9.  Relationships between psychological symptoms, somatic complaints and menopausal status.

Authors:  M Hunter; R Battersby; M Whitehead
Journal:  Maturitas       Date:  1986-10       Impact factor: 4.342

10.  Vaginal atrophy in the postmenopausal woman. The importance of sexual activity and hormones.

Authors:  S Leiblum; G Bachmann; E Kemmann; D Colburn; L Swartzman
Journal:  JAMA       Date:  1983 Apr 22-29       Impact factor: 56.272

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  55 in total

1.  Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive aging.

Authors:  Siobán D Harlow; Margery Gass; Janet E Hall; Roger Lobo; Pauline Maki; Robert W Rebar; Sherry Sherman; Patrick M Sluss; Tobie J de Villiers
Journal:  J Clin Endocrinol Metab       Date:  2012-02-16       Impact factor: 5.958

2.  Comparison of the Effects of Vaginal Royal Jelly and Vaginal Estrogen on Quality of Life, Sexual and Urinary Function in Postmenopausal Women.

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Journal:  J Clin Diagn Res       Date:  2016-05-01

3.  Association of sleep disturbance and sexual function in postmenopausal women.

Authors:  Juliana M Kling; JoAnn E Manson; Michelle J Naughton; M'hamed Temkit; Shannon D Sullivan; Emily W Gower; Lauren Hale; Julie C Weitlauf; Sara Nowakowski; Carolyn J Crandall
Journal:  Menopause       Date:  2017-06       Impact factor: 2.953

4.  Sisters Peer Counseling in Reproductive Issues After Treatment (SPIRIT): a peer counseling program to improve reproductive health among African American breast cancer survivors.

Authors:  Leslie R Schover; Michelle M Rhodes; George Baum; Jennifer Harned Adams; Rosell Jenkins; Pamela Lewis; Karen Eubanks Jackson
Journal:  Cancer       Date:  2011-04-14       Impact factor: 6.860

5.  Changes in sexual function among midlife women: "I'm older… and I'm wiser".

Authors:  Holly N Thomas; Megan Hamm; Rachel Hess; Rebecca C Thurston
Journal:  Menopause       Date:  2018-03       Impact factor: 2.953

Review 6.  Management of the Perimenopause.

Authors:  Lara Delamater; Nanette Santoro
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Review 7.  Female Sexual Function at Midlife and Beyond.

Authors:  Holly N Thomas; Genevieve S Neal-Perry; Rachel Hess
Journal:  Obstet Gynecol Clin North Am       Date:  2018-10-25       Impact factor: 2.844

8.  What midlife women want from gynecologists: a survey of patients in specialty and private practices.

Authors:  Beth A Prairie; Marcia Klein-Patel; MinJae Lee; Katherine L Wisner; Judith L Balk
Journal:  J Womens Health (Larchmt)       Date:  2014-01-09       Impact factor: 2.681

9.  Baseline characteristics and concerns of female cancer patients/survivors seeking treatment at a Female Sexual Medicine Program.

Authors:  Jeanne Carter; Cara Stabile; Barbara Seidel; Raymond E Baser; Abigail R Gunn; Stephanie Chi; Rebecca F Steed; Shari Goldfarb; Deborah J Goldfrank
Journal:  Support Care Cancer       Date:  2015-01-08       Impact factor: 3.603

10.  Sex, health, and years of sexually active life gained due to good health: evidence from two US population based cross sectional surveys of ageing.

Authors:  Stacy Tessler Lindau; Natalia Gavrilova
Journal:  BMJ       Date:  2010-03-09
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