| Literature DB >> 19211047 |
Abstract
Self-splicing group I introns come in two flavours - those with a homing endonuclease to promote mobility of the intron, and those without an endonuclease. How homing endonucleases and self-splicing introns associate to form a composite selfish genetic element is a question of long-standing interest. Recent work has revealed that a shared characteristic of both introns and endonucleases, the targeting of conserved sequences, may provide the impetus for the evolution of composite mobile genetic elements.Mesh:
Substances:
Year: 2009 PMID: 19211047 DOI: 10.1016/j.cub.2008.12.019
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834