Literature DB >> 19211047

Selfish DNA: homing endonucleases find a home.

David R Edgell1.   

Abstract

Self-splicing group I introns come in two flavours - those with a homing endonuclease to promote mobility of the intron, and those without an endonuclease. How homing endonucleases and self-splicing introns associate to form a composite selfish genetic element is a question of long-standing interest. Recent work has revealed that a shared characteristic of both introns and endonucleases, the targeting of conserved sequences, may provide the impetus for the evolution of composite mobile genetic elements.

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Year:  2009        PMID: 19211047     DOI: 10.1016/j.cub.2008.12.019

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  23 in total

1.  A group II intron encodes a functional LAGLIDADG homing endonuclease and self-splices under moderate temperature and ionic conditions.

Authors:  Sahra-Taylor Mullineux; Maria Costa; Gurminder S Bassi; François Michel; Georg Hausner
Journal:  RNA       Date:  2010-07-23       Impact factor: 4.942

Review 2.  Group I introns and inteins: disparate origins but convergent parasitic strategies.

Authors:  Rahul Raghavan; Michael F Minnick
Journal:  J Bacteriol       Date:  2009-08-07       Impact factor: 3.490

3.  A mitochondrial intron in a verongid sponge.

Authors:  Dirk Erpenbeck; Ratih Aryasari; John N A Hooper; Gert Wörheide
Journal:  J Mol Evol       Date:  2014-11-13       Impact factor: 2.395

4.  Evolutionary dynamics of the mS952 intron: a novel mitochondrial group II intron encoding a LAGLIDADG homing endonuclease gene.

Authors:  Sahra-Taylor Mullineux; Karla Willows; Georg Hausner
Journal:  J Mol Evol       Date:  2011-04-10       Impact factor: 2.395

5.  HNHDb: a database on pattern based classification of HNH domains reveals functional relevance of sequence patterns and domain associations.

Authors:  Alaguraj Veluchamy; Sujitha Mary; Vishal Acharya; Preethi Mehta; Taru Deva; Sankaran Krishnaswamy
Journal:  Bioinformation       Date:  2009-09-06

6.  The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo.

Authors:  Andreas Brachner; Juliane Braun; Medini Ghodgaonkar; Dennis Castor; Livija Zlopasa; Veronika Ehrlich; Josef Jiricny; Josef Gotzmann; Siegfried Knasmüller; Roland Foisner
Journal:  J Cell Sci       Date:  2012-03-07       Impact factor: 5.285

7.  Nucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signals.

Authors:  Livija Zlopasa; Andreas Brachner; Roland Foisner
Journal:  BMC Cell Biol       Date:  2016-06-01       Impact factor: 4.241

Review 8.  Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector-borne nematode diseases.

Authors:  Mostafa Zamanian; Erik C Andersen
Journal:  FEBS J       Date:  2016-07-11       Impact factor: 5.542

9.  A chimeric nuclease substitutes a phage CRISPR-Cas system to provide sequence-specific immunity against subviral parasites.

Authors:  Zachary K Barth; Maria Ht Nguyen; Kimberley D Seed
Journal:  Elife       Date:  2021-07-07       Impact factor: 8.713

10.  The monomeric GIY-YIG homing endonuclease I-BmoI uses a molecular anchor and a flexible tether to sequentially nick DNA.

Authors:  Benjamin P Kleinstiver; Jason M Wolfs; David R Edgell
Journal:  Nucleic Acids Res       Date:  2013-04-04       Impact factor: 16.971

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