Literature DB >> 19209316

Reversible molecular switching of molecular beacon: controlling DNA hybridization kinetics and thermodynamics using mercury(ii) ions.

Ronghua Yang1, Jianyu Jin, Liping Long, Yongxiang Wang, Hao Wang, Weihong Tan.   

Abstract

We report that the hydrogen-bonding pattern in a molecular beacon can be replaced by metal-dependent pairs of Hg(2+) and DNA thymine (T) bases. A molecular beacon based on T-Hg(2+)-T exhibits a lower background signal and higher thermostability than regular molecular beacons.

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Year:  2008        PMID： 19209316     DOI： 10.1039/b816638b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  Combating small molecule environmental contaminants: detection and sequestration using functional nucleic acids.

Authors:  Aimee A Sanford; Brea A Manuel; Misael A Romero-Reyes; Jennifer M Heemstra
Journal:  Chem Sci       Date:  2022-06-06       Impact factor: 9.969

2.  Reversible metal-dependent destabilization and stabilization of a stem-chelate-loop probe binding to an unmodified DNA target.

Authors:  Joel R Morgan; David V X Nguyen; Angela R Frohman; Sara R Rybka; John A Zebala
Journal:  Bioconjug Chem       Date:  2012-09-20       Impact factor: 4.774

3.  G-quadruplex DNAzyme molecular beacon for amplified colorimetric biosensing of Pseudostellaria heterophylla.

Authors:  Zhenzhu Zheng; Jing Han; Wensheng Pang; Juan Hu
Journal:  Sensors (Basel)       Date:  2013-01-16       Impact factor: 3.576

Review 4.  Molecular beacons of xeno-nucleic acid for detecting nucleic acid.

Authors:  Qi Wang; Lei Chen; Yitao Long; He Tian; Junchen Wu
Journal:  Theranostics       Date:  2013-05-05       Impact factor: 11.556
  4 in total

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