Literature DB >> 19208427

Identification of 12 or more lymph nodes in resected colon cancer specimens as an indicator of quality performance.

Robert O Dillman1, Kenneth Aaron, F Scott Heinemann, Stephanie E McClure.   

Abstract

BACKGROUND: : Identification of > or =12 lymph nodes in resected colon cancer specimens has been endorsed as a quality indicator.
METHODS: : The Hoag Hospital cancer registry was used to identify patients diagnosed with colon cancer. The proportion of colon cancer specimens for which > or =12 lymph nodes were identified was determined by anatomic location, stage of disease, patient age, and operating surgeon. Survival was correlated with stage and with whether > or =12 lymph nodes were identified.
RESULTS: : Pathology procedural changes in 1998 were associated with an increase in the average number of lymph nodes identified from 8.0 to 14.5 (P < .0001); therefore, analysis was limited to 574 patients who underwent surgical resection of colon adenocarcinoma during 1998 to 2005. Identification of > or =12 lymph nodes varied from 57% to 83% by 7 anatomic locations (P < .0001), from 65% to 75% by 5 age cohorts (P = .027), from 59% to 73% by 4 general stages of disease (P = .004), and from 53% to 80% among 12 surgeons who performed at least 17 resections (P = .014). The proportion of resections in which > or =12 lymph nodes were identified was higher for 3 colorectal fellowship-trained surgeons compared with the other 9 surgeons (77% vs 63%, P = .0007), and with 30 surgeons who each performed <10 resections (77% vs 51%, P < .0001). Identification of > or =12 lymph nodes was associated with better survival for patients with stage I (P = .016) and stage II (P = .021) disease.
CONCLUSIONS: : Anatomic location, colorectal surgical training, and case volume were strongly correlated with the number of lymph nodes identified. Cancer 2009. (c) 2009 American Cancer Society.

Entities:  

Mesh:

Year:  2009        PMID: 19208427     DOI: 10.1002/cncr.24185

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  22 in total

1.  Evaluation of lymph nodes in patients with colon cancer undergoing colon resection: a population-based study.

Authors:  Yun-Jau Chang; Yao-Jen Chang; Li-Ju Chen; Kuo-Piao Chung; Mei-Shu Lai
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2.  Complete mesocolic excision--a marker of surgical quality?

Authors:  Aisling M Hogan; Des C Winter
Journal:  J Gastrointest Surg       Date:  2009-08-05       Impact factor: 3.452

3.  [Quality indicators for colon cancer surgery : Evidence-based development of a set of indicators for the outcome quality].

Authors:  J Hardt; H-J Buhr; C Klinger; S Benz; K Ludwig; J Kalff; S Post
Journal:  Chirurg       Date:  2018-01       Impact factor: 0.955

4.  [Tumors of the lower gastrointestinal tract : Indication and extent of lymph node dissection].

Authors:  S Merkel; K Weber; A Perrakis; J Göhl; W Hohenberger
Journal:  Chirurg       Date:  2010-02       Impact factor: 0.955

5.  Age-dependent histoarchitectural changes in human lymph nodes: an underestimated process with clinical relevance?

Authors:  Catarina Hadamitzky; Hendrik Spohr; Anette S Debertin; Saskia Guddat; Michael Tsokos; Reinhard Pabst
Journal:  J Anat       Date:  2010-03-19       Impact factor: 2.610

6.  The Number of Natural Killer Cells in the Largest Diameter Lymph Nodes Is Associated with the Number of Retrieved Lymph Nodes and Lymph Node Size, and Is an Independent Prognostic Factor in Patients with Stage II Colon Cancer.

Authors:  Kazutake Okada; Sotaro Sadahiro; Lin Fung Chan; Takashi Ogimi; Hiroshi Miyakita; Gota Saito; Akira Tanaka; Toshiyuki Suzuki
Journal:  Oncology       Date:  2018-08-23       Impact factor: 2.935

Review 7.  Laparoscopic colon and rectal resections with intracorporeal anastomosis and trans-vaginal specimen extraction for colorectal cancer. A case series and systematic literature review.

Authors:  Francesco Stipa; Antonio Burza; Rosanna Curinga; Ettore Santini; Pietro Delle Site; Riccardo Avantifiori; Marcello Picchio
Journal:  Int J Colorectal Dis       Date:  2015-03-07       Impact factor: 2.571

8.  AC133 expression associated with poor prognosis in stage II colorectal cancer.

Authors:  Xiaofang Ying; Jiangxue Wu; Xiangqi Meng; Yufang Zuo; Qing Xia; Jinou Chen; Yanfen Feng; Ranyi Liu; Liren Li; Wenlin Huang
Journal:  Med Oncol       Date:  2013-01-16       Impact factor: 3.064

9.  Stage II colon cancer staging using the number of retrieved lymph nodes may be superior to current TNM staging for prognosis stratification: the Japanese study group for postoperative follow-up of colorectal cancer.

Authors:  Shimpei Ogawa; Michio Itabashi; Yoshiko Bamba; Kimitaka Tani; Shigeki Yamaguchi; Shinichi Yamauchi; Kenichi Sugihara
Journal:  Int J Colorectal Dis       Date:  2021-07-24       Impact factor: 2.571

10.  Remnant uptake as a postoperative oncologic quality indicator.

Authors:  David F Schneider; Kristin A Ojomo; Herbert Chen; Rebecca S Sippel
Journal:  Thyroid       Date:  2013-07-17       Impact factor: 6.568

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