Literature DB >> 19208315

Quality of life assessment in patients with locally advanced head and neck malignancy after ablative surgery and reconstruction with microvascular free flaps.

Taokeer Ahmed Rizvi1, Mamoon Rashid, Bashir Ahmed, Ehtesham Ul Haq, Saad-ur-Rahman Sarwar, Muhammad Zia-ul-Islam, Muhammad Sarmad Tamimy.   

Abstract

OBJECTIVE: To assess the improvement in Quality Of Life (QOL) after ablative surgery in locally advanced head and neck malignancies by microvascular free flaps reconstruction. STUDY
DESIGN: Quasi-experimental. PLACE AND DURATION OF STUDY: Department of Plastic Surgery, Combined Military Hospital, Rawalpindi, from September 2005 to February 2007.
METHODOLOGY: A total of 44 patients with locally advanced stage III and IV malignancy of head and neck were included in the study. All patients were treated with ablative surgery and reconstruction with microvascular free flaps. QOL was assessed by using a scoring questionnaire (including 5 parameters for extra oral cancers including physical and role function, body image, weight loss score and pain donor site morbidity; and an additional 5 parameters for intraoral tumours that included swallowing, speech, drooling of saliva and mouth opening). A high score indicated a poor QOL. Patients were assessed pre-operatively and then at 2, 4 and 6 months postoperatively.
RESULTS: Mean accumulative score and mean individual parameter scores for both extra- and intraoral tumours were significantly improved (p < 0.05).
CONCLUSION: Microvascular free flap reconstruction after ablative surgery in locally advanced head and neck malignancy had a profound impact on the improvement of QOL. There was an initial deterioration of physical scores postoperatively and postradiotherapy, followed by gradual improvement. By the end of 6 months, it surpassed the pre-operative QOL scores.

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Year:  2009        PMID: 19208315     DOI: 02.2009/JCPSP.108112

Source DB:  PubMed          Journal:  J Coll Physicians Surg Pak        ISSN: 1022-386X            Impact factor:   0.711


  4 in total

1.  Two-year quality of life after free flap reconstruction in tumor-site discrepancy among Taiwanese with moderately advanced oral squamous cell carcinoma.

Authors:  Kao-Ping Chang; Chung-Sheng Lai; Tung-Ying Hsieh; Yi-Chia Wu; Chih-Hau Chang
Journal:  World J Surg Oncol       Date:  2012-07-13       Impact factor: 2.754

Review 2.  Prognostic factors associated with a restricted mouth opening (trismus) in patients with head and neck cancer: Systematic review.

Authors:  Sarah J van der Geer; Phillip V van Rijn; Jan L N Roodenburg; Pieter U Dijkstra
Journal:  Head Neck       Date:  2020-06-18       Impact factor: 3.147

3.  Preservation of organ function in head and neck cancer.

Authors:  Uta Tschiesner
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2012-12-20

4.  Diagnostic and therapeutic features associated with modification of quality-of-life's outcomes between one and six months after major surgery for head and neck cancer.

Authors:  Margherita Gobbo; Federica Bullo; Giuseppe Perinetti; Annalisa Gatto; Giulia Ottaviani; Matteo Biasotto; Giancarlo Tirelli
Journal:  Braz J Otorhinolaryngol       Date:  2015-12-18
  4 in total

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