Literature DB >> 19207132

Baseline profiles of adolescent vs. adult-onset first-episode psychosis in an early detection program.

I Joa1, J O Johannessen, J Langeveld, S Friis, I Melle, S Opjordsmoen, E Simonsen, P Vaglum, T McGlashan, T K Larsen.   

Abstract

OBJECTIVE: Psychotic disorders often start in adolescence. We aim to investigate premorbid and baseline differences characterizing patients with an onset of psychosis in adolescence versus adulthood.
METHOD: We compare first-episode, DSM-IV non-affective psychosis with onset before (n = 43) and after (n = 189) 18 years on duration of untreated psychosis (DUP), level of symptoms, suicidal behaviour, and other baseline clinical and demographic characteristics.
RESULTS: Adolescent onset patients had poorer premorbid functioning, a longer DUP, higher suicidality, and more depressive symptoms. They also had better cognition, fewer psychotic symptoms, and were more likely to be treated on an out-patient basis.
CONCLUSION: Adolescents with first-episode psychosis may have a slower and more silent, i.e. insidious onset, and are at risk of experiencing longer treatment delays than adults. They fit the description of what used to be labeled process (versus reactive) schizophrenia.

Entities:  

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Year:  2009        PMID: 19207132     DOI: 10.1111/j.1600-0447.2008.01338.x

Source DB:  PubMed          Journal:  Acta Psychiatr Scand        ISSN: 0001-690X            Impact factor:   6.392


  18 in total

1.  Early detection and intervention of psychosis in children and adolescents: urgent need for studies.

Authors:  Benno G Schimmelmann; Frauke Schultze-Lutter
Journal:  Eur Child Adolesc Psychiatry       Date:  2012-05       Impact factor: 4.785

2.  A comparison of adolescent- and adult-onset first-episode, non-affective psychosis: 2-year follow-up.

Authors:  Johannes Langeveld; Inge Joa; Svein Friis; Wenche ten Velden Hegelstad; Ingrid Melle; Jan O Johannessen; Stein Opjordsmoen; Erik Simonsen; Per Vaglum; Bjørn Auestad; Thomas McGlashan; Tor K Larsen
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2012-03-23       Impact factor: 5.270

3.  Auditory sensory gating in young adolescents with early-onset psychosis: a comparison with attention deficit/hyperactivity disorder.

Authors:  Cecilie Koldbæk Lemvigh; Jens Richardt Møllegaard Jepsen; Birgitte Fagerlund; Anne Katrine Pagsberg; Birte Yding Glenthøj; Jacob Rydkjær; Bob Oranje
Journal:  Neuropsychopharmacology       Date:  2019-10-24       Impact factor: 7.853

Review 4.  Clinical high risk for psychosis in children and adolescents: a systematic review.

Authors:  Jordina Tor; Montserrat Dolz; Anna Sintes; Daniel Muñoz; Marta Pardo; Elena de la Serna; Olga Puig; Gisela Sugranyes; Inmaculada Baeza
Journal:  Eur Child Adolesc Psychiatry       Date:  2017-09-15       Impact factor: 4.785

5.  Identifying children and adolescents at ultra high risk of psychosis in Italian neuropsychiatry services: a feasibility study.

Authors:  Giulia Spada; S Molteni; C Pistone; M Chiappedi; P McGuire; P Fusar-Poli; U Balottin
Journal:  Eur Child Adolesc Psychiatry       Date:  2015-04-30       Impact factor: 4.785

6.  The 'at-risk mental state' for psychosis in adolescents: clinical presentation, transition and remission.

Authors:  Patrick Welsh; Paul A Tiffin
Journal:  Child Psychiatry Hum Dev       Date:  2014-02

7.  Duration of unspecific prodromal and clinical high risk states, and early help-seeking in first-admission psychosis patients.

Authors:  Frauke Schultze-Lutter; Jonas Rahman; Stephan Ruhrmann; Chantal Michel; Benno G Schimmelmann; Wolfgang Maier; Joachim Klosterkötter
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2015-07-09       Impact factor: 4.328

8.  Age at onset and clinical correlates in body dysmorphic disorder.

Authors:  Andri S Bjornsson; Elizabeth R Didie; Jon E Grant; William Menard; Emily Stalker; Katharine A Phillips
Journal:  Compr Psychiatry       Date:  2013-04-30       Impact factor: 3.735

Review 9.  Canadian Guidelines for the Pharmacological Treatment of Schizophrenia Spectrum and Other Psychotic Disorders in Children and Youth.

Authors:  Sabina Abidi; Irfan Mian; Iliana Garcia-Ortega; Tania Lecomte; Thomas Raedler; Kevin Jackson; Kim Jackson; Tamara Pringsheim; Donald Addington
Journal:  Can J Psychiatry       Date:  2017-08-02       Impact factor: 4.356

10.  Prevalence and clinical characteristics of patients with obsessive-compulsive disorder in first-episode psychosis.

Authors:  Kristen Hagen; Bjarne Hansen; Inge Joa; Tor Ketil Larsen
Journal:  BMC Psychiatry       Date:  2013-05-30       Impact factor: 3.630

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